STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRG2CProtein FRG2-like-2; FSHD region gene 2 family member C. (282 aa)    
Predicted Functional Partners:
ZNF354A
Zinc finger protein 354A; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.700
USP50
Inactive ubiquitin carboxyl-terminal hydrolase 50; Has no peptidase activity; Belongs to the peptidase C19 family.
      
 0.665
LIN54
Protein lin-54 homolog; Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context. In G0 phase, the complex binds to more than 800 promoters and is required for repression of E2F target genes. In S phase, the complex selectively binds to the promoters of G2/M genes whose products are required for mitosis and participates in their cell cycle dependent activation. In the complex, acts as a DNA-binding protein that binds the promoter of CDK1 in a sequence- specific manner. Specifically recognizes the consens [...]
      
 0.620
ZNF717
Zinc finger protein 717; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.611
FAM104B
Protein FAM104B; Family with sequence similarity 104 member B.
      
 0.515
OR2T27
Olfactory receptor 2T27; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.507
SP6
Transcription factor Sp6; Promotes cell proliferation; Belongs to the Sp1 C2H2-type zinc-finger protein family.
      
 0.475
KRTAP4-6
Keratin associated protein 4-6.
      
 0.446
NUTM2G
NUT family member 2G.
      
 0.446
ANKRD36C
Ankyrin repeat domain 36C.
      
 0.440
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.