node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FAM185A | TMEM134 | ENSP00000395340 | ENSP00000312615 | Protein FAM185A; Family with sequence similarity 185 member A. | Transmembrane protein 134. | 0.499 |
GPR152 | PPP1R26 | ENSP00000310255 | ENSP00000349274 | Probable G-protein coupled receptor 152; Orphan receptor. | Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. | 0.550 |
GPR152 | PTRH1 | ENSP00000310255 | ENSP00000418661 | Probable G-protein coupled receptor 152; Orphan receptor. | peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family. | 0.502 |
GPR152 | RNF170 | ENSP00000310255 | ENSP00000445725 | Probable G-protein coupled receptor 152; Orphan receptor. | E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. | 0.442 |
GPR152 | TMEM134 | ENSP00000310255 | ENSP00000312615 | Probable G-protein coupled receptor 152; Orphan receptor. | Transmembrane protein 134. | 0.477 |
GPR152 | TOR2A | ENSP00000310255 | ENSP00000362381 | Probable G-protein coupled receptor 152; Orphan receptor. | Torsin-2A; Torsin family 2 member A; Belongs to the ClpA/ClpB family. Torsin subfamily. | 0.454 |
IP6K1 | TMEM134 | ENSP00000482032 | ENSP00000312615 | Inositol hexakisphosphate kinase 1; Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4; Belongs to the inositol phosphokinase (IPK) family. | Transmembrane protein 134. | 0.584 |
IP6K1 | UBXN4 | ENSP00000482032 | ENSP00000272638 | Inositol hexakisphosphate kinase 1; Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4; Belongs to the inositol phosphokinase (IPK) family. | UBX domain-containing protein 4; Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD. | 0.785 |
PPP1R26 | GPR152 | ENSP00000349274 | ENSP00000310255 | Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. | Probable G-protein coupled receptor 152; Orphan receptor. | 0.550 |
PPP1R26 | PTRH1 | ENSP00000349274 | ENSP00000418661 | Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. | peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family. | 0.548 |
PPP1R26 | RNF170 | ENSP00000349274 | ENSP00000445725 | Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. | E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. | 0.429 |
PPP1R26 | TMEM134 | ENSP00000349274 | ENSP00000312615 | Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. | Transmembrane protein 134. | 0.489 |
PPP1R26 | TOR2A | ENSP00000349274 | ENSP00000362381 | Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. | Torsin-2A; Torsin family 2 member A; Belongs to the ClpA/ClpB family. Torsin subfamily. | 0.493 |
PTRH1 | GPR152 | ENSP00000418661 | ENSP00000310255 | peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family. | Probable G-protein coupled receptor 152; Orphan receptor. | 0.502 |
PTRH1 | PPP1R26 | ENSP00000418661 | ENSP00000349274 | peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family. | Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. | 0.548 |
PTRH1 | RNF170 | ENSP00000418661 | ENSP00000445725 | peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family. | E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. | 0.407 |
PTRH1 | TMEM134 | ENSP00000418661 | ENSP00000312615 | peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family. | Transmembrane protein 134. | 0.484 |
PTRH1 | TOR2A | ENSP00000418661 | ENSP00000362381 | peptidyl-tRNA hydrolase 1 homolog; Belongs to the PTH family. | Torsin-2A; Torsin family 2 member A; Belongs to the ClpA/ClpB family. Torsin subfamily. | 0.541 |
RNF170 | GPR152 | ENSP00000445725 | ENSP00000310255 | E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. | Probable G-protein coupled receptor 152; Orphan receptor. | 0.442 |
RNF170 | PPP1R26 | ENSP00000445725 | ENSP00000349274 | E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. | Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation. | 0.429 |