node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADPRHL1 | ZNF541 | ENSP00000364567 | ENSP00000375770 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1. | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. | 0.441 |
ARHGAP23 | CCDC51 | ENSP00000481862 | ENSP00000379047 | Rho GTPase-activating protein 23; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | Mitochondrial potassium channel; Mitochondrial potassium channel located in the mitochondrial inner membrane. Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP- dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume. | 0.508 |
ARHGAP23 | ZNF541 | ENSP00000481862 | ENSP00000375770 | Rho GTPase-activating protein 23; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. | 0.528 |
CCDC51 | ARHGAP23 | ENSP00000379047 | ENSP00000481862 | Mitochondrial potassium channel; Mitochondrial potassium channel located in the mitochondrial inner membrane. Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP- dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume. | Rho GTPase-activating protein 23; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.508 |
CCDC51 | ZNF541 | ENSP00000379047 | ENSP00000375770 | Mitochondrial potassium channel; Mitochondrial potassium channel located in the mitochondrial inner membrane. Together with ABCB8/MITOSUR, forms a protein complex localized in the mitochondria that mediates ATP- dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel). May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume. | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. | 0.534 |
DNTTIP1 | KCTD19 | ENSP00000361705 | ENSP00000305702 | Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA. | BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19. | 0.663 |
DNTTIP1 | ZNF541 | ENSP00000361705 | ENSP00000375770 | Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA. | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. | 0.726 |
KCTD19 | DNTTIP1 | ENSP00000305702 | ENSP00000361705 | BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19. | Deoxynucleotidyltransferase terminal-interacting protein 1; Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro). Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract. Associates with RAB20 promoter and positively regulates its transcription. Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA. | 0.663 |
KCTD19 | ZNF541 | ENSP00000305702 | ENSP00000375770 | BTB/POZ domain-containing protein KCTD19; Potassium channel tetramerization domain containing 19. | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. | 0.479 |
M0QYG6_HUMAN | ZNF541 | ENSP00000469811 | ENSP00000375770 | Uncharacterized protein. | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. | 0.581 |
POLD1 | RPS6KL1 | ENSP00000472445 | ENSP00000450567 | DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol-delta4), displays differences in catalytic activity. Most notably, expresses higher proo [...] | Ribosomal protein S6 kinase like 1. | 0.460 |
POLD1 | ZNF541 | ENSP00000472445 | ENSP00000375770 | DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol-delta4), displays differences in catalytic activity. Most notably, expresses higher proo [...] | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. | 0.490 |
POLD1 | ZNF710 | ENSP00000472445 | ENSP00000268154 | DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol-delta4), displays differences in catalytic activity. Most notably, expresses higher proo [...] | Zinc finger protein 710; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.507 |
RPS6KL1 | POLD1 | ENSP00000450567 | ENSP00000472445 | Ribosomal protein S6 kinase like 1. | DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol-delta4), displays differences in catalytic activity. Most notably, expresses higher proo [...] | 0.460 |
RPS6KL1 | SNRPN | ENSP00000450567 | ENSP00000494831 | Ribosomal protein S6 kinase like 1. | Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events. | 0.475 |
RPS6KL1 | ZNF541 | ENSP00000450567 | ENSP00000375770 | Ribosomal protein S6 kinase like 1. | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. | 0.680 |
RPS6KL1 | ZNF710 | ENSP00000450567 | ENSP00000268154 | Ribosomal protein S6 kinase like 1. | Zinc finger protein 710; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.672 |
SNRPN | RPS6KL1 | ENSP00000494831 | ENSP00000450567 | Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events. | Ribosomal protein S6 kinase like 1. | 0.475 |
SNRPN | ZNF541 | ENSP00000494831 | ENSP00000375770 | Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events. | Zinc finger protein 541; Component of some chromatin remodeling multiprotein complex that plays a role during spermatogenesis. | 0.504 |
SNRPN | ZNF710 | ENSP00000494831 | ENSP00000268154 | Small nuclear ribonucleoprotein-associated protein N; May be involved in tissue-specific alternative RNA processing events. | Zinc finger protein 710; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.501 |