STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABCF1ATP-binding cassette sub-family F member 1; Isoform 2 is required for efficient Cap- and IRES-mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis. (845 aa)    
Predicted Functional Partners:
RPL11
60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
   
 0.980
RPS23
40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
  
 0.962
RPL10A
60S ribosomal protein L10a; Component of the large ribosomal subunit.
   
 0.953
RPL8
60S ribosomal protein L8; Component of the large ribosomal subunit.
   
 0.952
RPS29
Ribosomal protein S29.
   
  0.952
RPL19
Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.
   
 0.947
RPS28
Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family.
   
 0.943
RPL18
60S ribosomal protein L18; Component of the large ribosomal subunit.
   
 0.934
RPL38
Ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.
   
  0.929
RPS21
Ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.
   
  0.924
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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