node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MPHOSPH10 | NOL6 | ENSP00000244230 | ENSP00000297990 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | Nucleolar protein 6; Belongs to the NRAP family. | 0.999 |
MPHOSPH10 | NOP58 | ENSP00000244230 | ENSP00000264279 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs. Belongs to the NOP5/NOP56 family. | 0.999 |
MPHOSPH10 | RRP9 | ENSP00000244230 | ENSP00000232888 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | U3 small nucleolar RNA-interacting protein 2; Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (pre-rRNA). | 0.999 |
MPHOSPH10 | UTP15 | ENSP00000244230 | ENSP00000296792 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | U3 small nucleolar RNA-associated protein 15 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. | 0.999 |
MPHOSPH10 | UTP18 | ENSP00000244230 | ENSP00000225298 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family. | 0.999 |
MPHOSPH10 | UTP20 | ENSP00000244230 | ENSP00000261637 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | Small subunit processome component 20 homolog; Involved in 18S pre-rRNA processing. Associates with U3 snoRNA. | 0.997 |
MPHOSPH10 | UTP4 | ENSP00000244230 | ENSP00000327179 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | U3 small nucleolar RNA-associated protein 4 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b. Required for optimal pre- ribosomal RNA transcription by RNA polymerase. May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5'-GGGACTTTCC-3' found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV. | 0.999 |
MPHOSPH10 | UTP6 | ENSP00000244230 | ENSP00000261708 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family. | 0.999 |
MPHOSPH10 | WDR3 | ENSP00000244230 | ENSP00000308179 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | WD repeat domain 3; Belongs to the WD repeat WDR3/UTP12 family. | 0.999 |
MPHOSPH10 | WDR75 | ENSP00000244230 | ENSP00000314193 | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. | 0.999 |
NOL6 | MPHOSPH10 | ENSP00000297990 | ENSP00000244230 | Nucleolar protein 6; Belongs to the NRAP family. | U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing. | 0.999 |
NOL6 | NOP58 | ENSP00000297990 | ENSP00000264279 | Nucleolar protein 6; Belongs to the NRAP family. | Nucleolar protein 58; Required for 60S ribosomal subunit biogenesis (By similarity). Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs. Belongs to the NOP5/NOP56 family. | 0.999 |
NOL6 | RRP9 | ENSP00000297990 | ENSP00000232888 | Nucleolar protein 6; Belongs to the NRAP family. | U3 small nucleolar RNA-interacting protein 2; Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (pre-rRNA). | 0.999 |
NOL6 | UTP15 | ENSP00000297990 | ENSP00000296792 | Nucleolar protein 6; Belongs to the NRAP family. | U3 small nucleolar RNA-associated protein 15 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. | 0.998 |
NOL6 | UTP18 | ENSP00000297990 | ENSP00000225298 | Nucleolar protein 6; Belongs to the NRAP family. | U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family. | 0.999 |
NOL6 | UTP20 | ENSP00000297990 | ENSP00000261637 | Nucleolar protein 6; Belongs to the NRAP family. | Small subunit processome component 20 homolog; Involved in 18S pre-rRNA processing. Associates with U3 snoRNA. | 0.999 |
NOL6 | UTP4 | ENSP00000297990 | ENSP00000327179 | Nucleolar protein 6; Belongs to the NRAP family. | U3 small nucleolar RNA-associated protein 4 homolog; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Involved in small subunit (SSU) pre-rRNA processing at sites A', A0, 1 and 2b. Required for optimal pre- ribosomal RNA transcription by RNA polymerase. May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5'-GGGACTTTCC-3' found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV. | 0.999 |
NOL6 | UTP6 | ENSP00000297990 | ENSP00000261708 | Nucleolar protein 6; Belongs to the NRAP family. | U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family. | 0.999 |
NOL6 | WDR3 | ENSP00000297990 | ENSP00000308179 | Nucleolar protein 6; Belongs to the NRAP family. | WD repeat domain 3; Belongs to the WD repeat WDR3/UTP12 family. | 0.999 |
NOL6 | WDR75 | ENSP00000297990 | ENSP00000314193 | Nucleolar protein 6; Belongs to the NRAP family. | WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. | 0.999 |