Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MRPL1Mitochondrial ribosomal protein L1. (325 aa)    
Predicted Functional Partners:
MRPL10
Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family.
   
 
 0.999
MRPL39
Mitochondrial ribosomal protein L39; Belongs to the mitochondrion-specific ribosomal protein mL39 family.
   
 
 0.999
MRPL13
Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.
  
 
 0.999
MRPL4
Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family.
  
 
 0.999
MRPL52
Mitochondrial ribosomal protein L52.
   
 
 0.999
MRPL41
39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.
   
 
 0.999
MRPS30
Mitochondrial ribosomal protein S30.
   
 
 0.999
MRPL42
Mitochondrial ribosomal protein L42; Belongs to the mitochondrion-specific ribosomal protein mL42 family.
   
 
 0.999
MRPL12
39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family.
  
 
 0.998
MRPL47
Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family.
   
 
 0.998
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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