STRINGSTRING
KDELC2 protein (human) - STRING interaction network
"KDELC2" - KDEL motif-containing protein 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KDELC2KDEL motif-containing protein 2; Glycosyltransferase family 90; Belongs to the KDELC family (507 aa)    
Predicted Functional Partners:
C11orf65
Uncharacterized protein C11orf65; Chromosome 11 open reading frame 65 (313 aa)
 
       
  0.814
TMEM40
Transmembrane protein 40 (233 aa)
           
  0.701
EXPH5
Exophilin-5; May act as Rab effector protein and play a role in vesicle trafficking (1989 aa)
           
  0.684
ELMOD1
ELMO domain-containing protein 1; Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family (334 aa)
           
  0.600
GRAMD1B
GRAM domain containing 1B (745 aa)
     
   
  0.600
NPAT
Protein NPAT; Required for progression through the G1 and S phases of the cell cycle and for S phase entry. Activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. Also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters; Belongs to the NPAT family (1427 aa)
           
  0.571
GXYLT2
Glucoside xylosyltransferase 2; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose; Glycosyltransferase family 8 (443 aa)
           
  0.569
SLC35F2
Solute carrier family 35 member F2; Putative solute transporter (374 aa)
           
  0.558
TNFAIP8L3
Tumor necrosis factor alpha-induced protein 8-like protein 3; Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling; Belongs to the TNFAIP8 family (292 aa)
           
  0.551
CSMD2
CUB and Sushi multiple domains 2 (3631 aa)
           
  0.537
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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