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TMEM25 protein (human) - STRING interaction network
"TMEM25" - Transmembrane protein 25 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM25Transmembrane protein 25; C2-set domain containing (366 aa)    
Predicted Functional Partners:
ZDHHC8
Probable palmitoyltransferase ZDHHC8; Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily (778 aa)
     
   
  0.676
HGD
Homogentisate 1,2-dioxygenase (445 aa)
     
   
  0.577
TMEM30B
Cell cycle control protein 50B; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to th [...] (351 aa)
     
   
  0.548
SLC35G2
Solute carrier family 35 member G2; May play a role in cell proliferation; Solute carriers (412 aa)
           
  0.531
AMZ1
Archaemetzincin-1; Zinc metalloprotease. Exhibits aminopeptidase activity against neurogranin in vitro. Does not hydrolyze angiotensin-2; Belongs to the peptidase M54 family (498 aa)
           
  0.523
LPPR5
Phospholipid phosphatase-related protein type 5; Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory- mediated axonal retraction; Belongs to the PA-phosphatase related phosphoesterase family (321 aa)
           
  0.514
EIF5A2
Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By s [...] (153 aa)
           
  0.507
FAM172A
Protein FAM172A; Family with sequence similarity 172 member A; Belongs to the UPF0528 family (416 aa)
           
  0.501
ZSCAN18
Zinc finger and SCAN domain-containing protein 18; May be involved in transcriptional regulation; SCAN domain containing (566 aa)
     
   
  0.486
MEIG1
Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis (88 aa)
           
  0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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