node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCNC | ZNF18 | ENSP00000428982 | ENSP00000315664 | Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase CDK8 that phosphoryla [...] | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.655 |
NCKAP5L | UBE3B | ENSP00000337998 | ENSP00000340596 | Nck-associated protein 5-like; Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylation of microtubules. Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation. | Ubiquitin-protein ligase E3B; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | 0.582 |
NCKAP5L | ZNF18 | ENSP00000337998 | ENSP00000315664 | Nck-associated protein 5-like; Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylation of microtubules. Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation. | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.669 |
SCAND1 | ZNF174 | ENSP00000363103 | ENSP00000268655 | SCAN domain-containing protein 1; May regulate transcriptional activity. | Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.753 |
SCAND1 | ZNF18 | ENSP00000363103 | ENSP00000315664 | SCAN domain-containing protein 1; May regulate transcriptional activity. | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.704 |
SCAND1 | ZNF24 | ENSP00000363103 | ENSP00000382015 | SCAN domain-containing protein 1; May regulate transcriptional activity. | Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.857 |
SCAND1 | ZNF483 | ENSP00000363103 | ENSP00000311679 | SCAN domain-containing protein 1; May regulate transcriptional activity. | Zinc finger protein 483; May be involved in transcriptional regulation. | 0.684 |
TTC32 | ZNF18 | ENSP00000333018 | ENSP00000315664 | Tetratricopeptide repeat domain 32. | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.628 |
UBE3B | NCKAP5L | ENSP00000340596 | ENSP00000337998 | Ubiquitin-protein ligase E3B; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Nck-associated protein 5-like; Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylation of microtubules. Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation. | 0.582 |
UBE3B | ZNF18 | ENSP00000340596 | ENSP00000315664 | Ubiquitin-protein ligase E3B; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.719 |
ZBTB24 | ZNF18 | ENSP00000230122 | ENSP00000315664 | Zinc finger and BTB domain-containing protein 24; May be involved in BMP2-induced transcription. | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.602 |
ZNF174 | SCAND1 | ENSP00000268655 | ENSP00000363103 | Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. | SCAN domain-containing protein 1; May regulate transcriptional activity. | 0.753 |
ZNF174 | ZNF18 | ENSP00000268655 | ENSP00000315664 | Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.798 |
ZNF174 | ZNF24 | ENSP00000268655 | ENSP00000382015 | Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 24; Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence (By similarity). Has transcription repressor activity in vitro; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.864 |
ZNF174 | ZNF446 | ENSP00000268655 | ENSP00000472802 | Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 446; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.590 |
ZNF174 | ZNF483 | ENSP00000268655 | ENSP00000311679 | Zinc finger protein 174; Transcriptional repressor; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 483; May be involved in transcriptional regulation. | 0.620 |
ZNF18 | CCNC | ENSP00000315664 | ENSP00000428982 | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Cyclin-C; Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin- dependent kinase CDK8 that phosphoryla [...] | 0.655 |
ZNF18 | NCKAP5L | ENSP00000315664 | ENSP00000337998 | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Nck-associated protein 5-like; Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylation of microtubules. Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation. | 0.669 |
ZNF18 | SCAND1 | ENSP00000315664 | ENSP00000363103 | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | SCAN domain-containing protein 1; May regulate transcriptional activity. | 0.704 |
ZNF18 | TTC32 | ENSP00000315664 | ENSP00000333018 | Zinc finger protein 18; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Tetratricopeptide repeat domain 32. | 0.628 |