node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf159 | DNHD1 | ENSP00000368644 | ENSP00000254579 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159. | Dynein heavy chain domain 1. | 0.540 |
C1orf159 | PROM2 | ENSP00000368644 | ENSP00000318270 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159. | Prominin-2; Prominin 2. | 0.459 |
C1orf159 | PTCD2 | ENSP00000368644 | ENSP00000370013 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159. | Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function. | 0.527 |
C1orf159 | ZNF106 | ENSP00000368644 | ENSP00000263805 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159. | Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism. | 0.506 |
C1orf159 | ZNHIT2 | ENSP00000368644 | ENSP00000308548 | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159. | Zinc finger HIT domain-containing protein 2; May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 snRNP). Required for the interaction of R2TP complex subunit RPAP3 and prefoldin-like subunit URI1 with U5 snRNP proteins EFTUD2 and PRPF8. May play a role in regulating the composition of the U5 snRNP complex. | 0.536 |
CISD1 | NCOA4 | ENSP00000363041 | ENSP00000463027 | CDGSH iron-sulfur domain-containing protein 1; Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family. | Nuclear receptor coactivator 4; Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. | 0.592 |
CISD1 | PROM2 | ENSP00000363041 | ENSP00000318270 | CDGSH iron-sulfur domain-containing protein 1; Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family. | Prominin-2; Prominin 2. | 0.417 |
CISD1 | SLC40A1 | ENSP00000363041 | ENSP00000261024 | CDGSH iron-sulfur domain-containing protein 1; Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family. | Solute carrier family 40 member 1; May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin); Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. | 0.466 |
DNHD1 | C1orf159 | ENSP00000254579 | ENSP00000368644 | Dynein heavy chain domain 1. | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159. | 0.540 |
DNHD1 | PROM2 | ENSP00000254579 | ENSP00000318270 | Dynein heavy chain domain 1. | Prominin-2; Prominin 2. | 0.433 |
DNHD1 | PTCD2 | ENSP00000254579 | ENSP00000370013 | Dynein heavy chain domain 1. | Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function. | 0.489 |
DNHD1 | ZNF106 | ENSP00000254579 | ENSP00000263805 | Dynein heavy chain domain 1. | Zinc finger protein 106; RNA-binding protein. Specifically binds to 5'-GGGGCC-3' sequence repeats in RNA. Essential for maintenance of peripheral motor neuron and skeletal muscle function. Required for normal expression and/or alternative splicing of a number of genes in spinal cord and skeletal muscle, including the neurite outgrowth inhibitor RTN4. Also contributes to normal mitochondrial respiratory function in motor neurons, via an unknown mechanism. | 0.473 |
DNHD1 | ZNHIT2 | ENSP00000254579 | ENSP00000308548 | Dynein heavy chain domain 1. | Zinc finger HIT domain-containing protein 2; May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 snRNP). Required for the interaction of R2TP complex subunit RPAP3 and prefoldin-like subunit URI1 with U5 snRNP proteins EFTUD2 and PRPF8. May play a role in regulating the composition of the U5 snRNP complex. | 0.485 |
MTF1 | PROM2 | ENSP00000362127 | ENSP00000318270 | Metal regulatory transcription factor 1; Activates the metallothionein I promoter. Binds to the metal responsive element (MRE). | Prominin-2; Prominin 2. | 0.432 |
MTF1 | SLC40A1 | ENSP00000362127 | ENSP00000261024 | Metal regulatory transcription factor 1; Activates the metallothionein I promoter. Binds to the metal responsive element (MRE). | Solute carrier family 40 member 1; May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin); Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. | 0.426 |
NCOA4 | CISD1 | ENSP00000463027 | ENSP00000363041 | Nuclear receptor coactivator 4; Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. | CDGSH iron-sulfur domain-containing protein 1; Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family. | 0.592 |
NCOA4 | PROM2 | ENSP00000463027 | ENSP00000318270 | Nuclear receptor coactivator 4; Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. | Prominin-2; Prominin 2. | 0.463 |
NCOA4 | SLC40A1 | ENSP00000463027 | ENSP00000261024 | Nuclear receptor coactivator 4; Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma. | Solute carrier family 40 member 1; May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin); Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. | 0.599 |
PROM2 | C1orf159 | ENSP00000318270 | ENSP00000368644 | Prominin-2; Prominin 2. | Uncharacterized protein C1orf159; Chromosome 1 open reading frame 159. | 0.459 |
PROM2 | CISD1 | ENSP00000318270 | ENSP00000363041 | Prominin-2; Prominin 2. | CDGSH iron-sulfur domain-containing protein 1; Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions. Belongs to the CISD protein family. | 0.417 |