node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B3GALT4 | B4GALT6 | ENSP00000390784 | ENSP00000306459 | Beta-1,3-galactosyltransferase 4; Involved in GM1/GD1B/GA1 ganglioside biosynthesis. | Beta-1,4-galactosyltransferase 6; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Belongs to the glycosyltransferase 7 family. | 0.706 |
B3GALT4 | ST3GAL5 | ENSP00000390784 | ENSP00000491316 | Beta-1,3-galactosyltransferase 4; Involved in GM1/GD1B/GA1 ganglioside biosynthesis. | Lactosylceramide alpha-2,3-sialyltransferase; Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide). | 0.646 |
B3GALT4 | ST6GALNAC5 | ENSP00000390784 | ENSP00000417583 | Beta-1,3-galactosyltransferase 4; Involved in GM1/GD1B/GA1 ganglioside biosynthesis. | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; Involved in the biosynthesis of ganglioside GD1a from GM1b. It exhibits higher activity with glycolipids than with glycoproteins (By similarity). | 0.413 |
B3GALT4 | ST8SIA5 | ENSP00000390784 | ENSP00000445492 | Beta-1,3-galactosyltransferase 4; Involved in GM1/GD1B/GA1 ganglioside biosynthesis. | Alpha-2,8-sialyltransferase 8E; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively. Belongs to the glycosyltransferase 29 family. | 0.644 |
B4GALT6 | B3GALT4 | ENSP00000306459 | ENSP00000390784 | Beta-1,4-galactosyltransferase 6; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Belongs to the glycosyltransferase 7 family. | Beta-1,3-galactosyltransferase 4; Involved in GM1/GD1B/GA1 ganglioside biosynthesis. | 0.706 |
B4GALT6 | ST3GAL5 | ENSP00000306459 | ENSP00000491316 | Beta-1,4-galactosyltransferase 6; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Belongs to the glycosyltransferase 7 family. | Lactosylceramide alpha-2,3-sialyltransferase; Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide). | 0.951 |
B4GALT6 | ST8SIA5 | ENSP00000306459 | ENSP00000445492 | Beta-1,4-galactosyltransferase 6; Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Belongs to the glycosyltransferase 7 family. | Alpha-2,8-sialyltransferase 8E; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively. Belongs to the glycosyltransferase 29 family. | 0.553 |
BEND7 | KATNAL2 | ENSP00000345773 | ENSP00000245121 | BEN domain containing 7. | Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. | 0.489 |
BEND7 | LOXHD1 | ENSP00000345773 | ENSP00000444586 | BEN domain containing 7. | Lipoxygenase homology domain-containing protein 1; Involved in hearing. Required for normal function of hair cells in the inner ear (By similarity). | 0.441 |
BEND7 | ST8SIA5 | ENSP00000345773 | ENSP00000445492 | BEN domain containing 7. | Alpha-2,8-sialyltransferase 8E; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively. Belongs to the glycosyltransferase 29 family. | 0.507 |
BEND7 | TATDN3 | ENSP00000345773 | ENSP00000431376 | BEN domain containing 7. | Putative deoxyribonuclease TATDN3; Putative deoxyribonuclease; Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. | 0.625 |
KATNAL2 | BEND7 | ENSP00000245121 | ENSP00000345773 | Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. | BEN domain containing 7. | 0.489 |
KATNAL2 | LOXHD1 | ENSP00000245121 | ENSP00000444586 | Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. | Lipoxygenase homology domain-containing protein 1; Involved in hearing. Required for normal function of hair cells in the inner ear (By similarity). | 0.457 |
KATNAL2 | ST8SIA5 | ENSP00000245121 | ENSP00000445492 | Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. | Alpha-2,8-sialyltransferase 8E; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively. Belongs to the glycosyltransferase 29 family. | 0.554 |
KATNAL2 | TATDN3 | ENSP00000245121 | ENSP00000431376 | Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. | Putative deoxyribonuclease TATDN3; Putative deoxyribonuclease; Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. | 0.553 |
LOXHD1 | BEND7 | ENSP00000444586 | ENSP00000345773 | Lipoxygenase homology domain-containing protein 1; Involved in hearing. Required for normal function of hair cells in the inner ear (By similarity). | BEN domain containing 7. | 0.441 |
LOXHD1 | KATNAL2 | ENSP00000444586 | ENSP00000245121 | Lipoxygenase homology domain-containing protein 1; Involved in hearing. Required for normal function of hair cells in the inner ear (By similarity). | Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. | 0.457 |
LOXHD1 | ST8SIA5 | ENSP00000444586 | ENSP00000445492 | Lipoxygenase homology domain-containing protein 1; Involved in hearing. Required for normal function of hair cells in the inner ear (By similarity). | Alpha-2,8-sialyltransferase 8E; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively. Belongs to the glycosyltransferase 29 family. | 0.571 |
LOXHD1 | TATDN3 | ENSP00000444586 | ENSP00000431376 | Lipoxygenase homology domain-containing protein 1; Involved in hearing. Required for normal function of hair cells in the inner ear (By similarity). | Putative deoxyribonuclease TATDN3; Putative deoxyribonuclease; Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. | 0.513 |
NANP | ST8SIA5 | ENSP00000302441 | ENSP00000445492 | N-acylneuraminate-9-phosphatase; N-acetylneuraminic acid phosphatase. | Alpha-2,8-sialyltransferase 8E; May be involved in the synthesis of gangliosides GD1c, GT1a, GQ1b and GT3 from GD1a, GT1b, GM1b and GD3 respectively. Belongs to the glycosyltransferase 29 family. | 0.528 |