Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NKPD1NTPase KAP family P-loop domain containing 1. (610 aa)    
Predicted Functional Partners:
TRAPPC6A
Trafficking protein particle complex subunit 6A; May play a role in vesicular transport during the biogenesis of melanosomes.
 
  
 
 0.551
ZNF34
Zinc finger protein 34; May be involved in transcriptional regulation.
      
 0.549
PPP1R37
Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.
      
 0.507
CLPTM1
Cleft lip and palate transmembrane protein 1; May play a role in T-cell development; Belongs to the CLPTM1 family.
    
 
 0.445
IGSF23
Immunoglobulin superfamily member 23.
      
 0.422
CLASRP
CLK4-associating serine/arginine rich protein; Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family (By similarity).
      
 0.420
TMEM169
Transmembrane protein 169.
      
 0.402
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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