STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C4orf17Uncharacterized protein C4orf17; Chromosome 4 open reading frame 17. (359 aa)    
Predicted Functional Partners:
LKAAEAR1
Protein LKAAEAR1; LKAAEAR motif containing 1.
   
  
 0.670
ZNF512
Zinc finger protein 512; May be involved in transcriptional regulation.
      
 0.578
ARRDC5
Arrestin domain containing 5; Belongs to the arrestin family.
      
 0.507
NT5C1B-RDH14
NT5C1B-RDH14 readthrough.
      
 0.446
NT5C1B
Cytosolic 5'-nucleotidase 1B; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity).
   
  
 0.441
DNAJC17
DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription.
      
 0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.