node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LIMD2 | ZNF771 | ENSP00000259006 | ENSP00000323945 | LIM domain-containing protein 2; Acts as an activator of the protein-kinase ILK, thereby regulating cell motility. | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.460 |
MALSU1 | ZNF771 | ENSP00000419370 | ENSP00000323945 | Mitochondrial assembly of ribosomal large subunit protein 1; Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of [...] | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.442 |
QSER1 | ZNF771 | ENSP00000382241 | ENSP00000323945 | Glutamine and serine rich 1. | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.401 |
RCOR3 | ZNF771 | ENSP00000413929 | ENSP00000323945 | REST corepressor 3; May act as a component of a corepressor complex that represses transcription; Belongs to the CoREST family. | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.477 |
RPL30 | ZNF593 | ENSP00000428085 | ENSP00000363384 | Ribosomal protein L30. | Zinc finger protein 593; Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins. | 0.914 |
RPL30 | ZNF771 | ENSP00000428085 | ENSP00000323945 | Ribosomal protein L30. | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.416 |
TRIM28 | ZNF771 | ENSP00000253024 | ENSP00000323945 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.555 |
ZNF593 | RPL30 | ENSP00000363384 | ENSP00000428085 | Zinc finger protein 593; Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins. | Ribosomal protein L30. | 0.914 |
ZNF593 | ZNF771 | ENSP00000363384 | ENSP00000323945 | Zinc finger protein 593; Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins. | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.408 |
ZNF771 | LIMD2 | ENSP00000323945 | ENSP00000259006 | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | LIM domain-containing protein 2; Acts as an activator of the protein-kinase ILK, thereby regulating cell motility. | 0.460 |
ZNF771 | MALSU1 | ENSP00000323945 | ENSP00000419370 | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Mitochondrial assembly of ribosomal large subunit protein 1; Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits (Probable). Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits (Probable). Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of [...] | 0.442 |
ZNF771 | QSER1 | ENSP00000323945 | ENSP00000382241 | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Glutamine and serine rich 1. | 0.401 |
ZNF771 | RCOR3 | ENSP00000323945 | ENSP00000413929 | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | REST corepressor 3; May act as a component of a corepressor complex that represses transcription; Belongs to the CoREST family. | 0.477 |
ZNF771 | RPL30 | ENSP00000323945 | ENSP00000428085 | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Ribosomal protein L30. | 0.416 |
ZNF771 | TRIM28 | ENSP00000323945 | ENSP00000253024 | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.555 |
ZNF771 | ZNF593 | ENSP00000323945 | ENSP00000363384 | Zinc finger protein 771; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 593; Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins. | 0.408 |