ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface le [...]

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface le [...]

Tripartite motif containing 67; Belongs to the TRIM/RBCC family.

Arylamine N-acetyltransferase 2; Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.

Transmembrane protein 161B; Belongs to the TMEM161 family.

GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.

Tripartite motif containing 67; Belongs to the TRIM/RBCC family.

GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.

Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface le [...]

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

Arylamine N-acetyltransferase 2; Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

Transmembrane protein 161B; Belongs to the TMEM161 family.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

Tripartite motif containing 67; Belongs to the TRIM/RBCC family.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

Protein virilizer homolog; Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs in the 3'-UTR near the stop codon: recruits the catalytic core components METTL3 and METTL14, thereby guiding m6A methylation at specific sites. Required for mRNA polyadenylation via its role in selective m6A methylation: m6A methylation of mRNAs in the 3'-UTR near the stop codon corr [...]

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

Exportin-7; Mediates the nuclear export of proteins (cargos) with broad substrate specificity. In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO7 then return to the nuclear compartment and mediate ano [...]

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

14-3-3 protein eta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6.

Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

Tripartite motif containing 67; Belongs to the TRIM/RBCC family.

Transmembrane protein 161B; Belongs to the TMEM161 family.

GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.