LRRN4CL protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIG	LRRN4CL	ENSP00000440331	ENSP00000325808	Adipogenin; Plays a role in stimulating adipocyte differentiation and development; Belongs to the adipogenin family.	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	0.539
CDCA4	LRRN4CL	ENSP00000337226	ENSP00000325808	Cell division cycle-associated protein 4; May participate in the regulation of cell proliferation through the E2F/RB pathway. May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation (By similarity).	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	0.408
LRRN4CL	ADIG	ENSP00000325808	ENSP00000440331	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	Adipogenin; Plays a role in stimulating adipocyte differentiation and development; Belongs to the adipogenin family.	0.539
LRRN4CL	CDCA4	ENSP00000325808	ENSP00000337226	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	Cell division cycle-associated protein 4; May participate in the regulation of cell proliferation through the E2F/RB pathway. May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation (By similarity).	0.408
LRRN4CL	PDCL2	ENSP00000325808	ENSP00000295645	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	Phosducin-like protein 2; May play a role in germ cell maturation; Belongs to the phosducin family.	0.438
LRRN4CL	SRPK2	ENSP00000325808	ENSP00000377262	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	SRSF protein kinase 2 C-terminal; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates [...]	0.457
LRRN4CL	TRIM67	ENSP00000325808	ENSP00000355613	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	Tripartite motif containing 67; Belongs to the TRIM/RBCC family.	0.457
PDCL2	LRRN4CL	ENSP00000295645	ENSP00000325808	Phosducin-like protein 2; May play a role in germ cell maturation; Belongs to the phosducin family.	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	0.438
SRPK2	LRRN4CL	ENSP00000377262	ENSP00000325808	SRSF protein kinase 2 C-terminal; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates [...]	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	0.457
SRPK2	TRIM67	ENSP00000377262	ENSP00000355613	SRSF protein kinase 2 C-terminal; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates [...]	Tripartite motif containing 67; Belongs to the TRIM/RBCC family.	0.457
TRIM67	LRRN4CL	ENSP00000355613	ENSP00000325808	Tripartite motif containing 67; Belongs to the TRIM/RBCC family.	LRRN4 C-terminal-like protein; LRRN4 C-terminal like.	0.457
TRIM67	SRPK2	ENSP00000355613	ENSP00000377262	Tripartite motif containing 67; Belongs to the TRIM/RBCC family.	SRSF protein kinase 2 C-terminal; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates [...]	0.457