STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTBDNRetbindin; Riboflavin-binding protein which might have a role in retinal flavin transport (261 aa)    
Predicted Functional Partners:
TTC9B
Tetratricopeptide repeat domain containing
   
  
 0.584
ERICH1
Glutamate-rich protein 1; Glutamate rich 1
      
 0.539
TMEM129
E3 ubiquitin-protein ligase TM129; E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2. Exploited by viral US11 proteins to mediate HLA class I proteins degradation
      
 0.499
C16orf93
Coiled-coil domain-containing protein 189; Chromosome 16 open reading frame 93
      
 0.495
ZNF668
Zinc finger protein 668; May be involved in transcriptional regulation; Zinc fingers C2H2-type
      
 0.484
PI15
Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity); Belongs to the CRISP family
      
 0.465
OPTC
Opticin; Binds collagen fibrils; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily
      
 0.444
LGSN
Lengsin; May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have enzymatic activity (By similarity); Belongs to the glutamine synthetase family
      
 0.443
BCL7C
B-cell CLL/lymphoma 7 protein family member C; May play an anti-apoptotic role; BAF complex
      
 0.442
ARRDC2
Arrestin domain containing 2; Belongs to the arrestin family
      
 0.441
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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