STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM71F1Protein FAM71F1; Family with sequence similarity 71 member F1. (344 aa)    
Predicted Functional Partners:
TEX33
Testis-expressed protein 33; Testis expressed 33.
  
  
 0.643
SPATA3
Spermatogenesis-associated protein 3; Spermatogenesis associated 3.
   
  
 0.643
TMEM225
Transmembrane protein 225; Probably inhibits protein phosphatase 1 (PP1) in sperm via binding to catalytic subunit PPP1CC.
   
  
 0.629
SPACA4
Sperm acrosome membrane-associated protein 4; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization.
      
 0.623
ODF1
Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.
  
  
 0.606
C22orf23
UPF0193 protein EVG1; Chromosome 22 open reading frame 23.
   
  
 0.586
TMEM270
Transmembrane protein 270.
   
  
 0.584
UBQLN3
Ubiquilin-3; Ubiquilin 3.
   
 
 0.573
AKAP4
A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family.
  
  
 0.555
C12orf50
Uncharacterized protein C12orf50; Chromosome 12 open reading frame 50.
  
  
 0.547
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.