STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMCO5ATransmembrane and coiled-coil domains 5A; Belongs to the TMCO5 family. (288 aa)    
Predicted Functional Partners:
FAM209A
Protein FAM209A; Family with sequence similarity 209 member A.
      
 0.705
TMEM225
Transmembrane protein 225; Probably inhibits protein phosphatase 1 (PP1) in sperm via binding to catalytic subunit PPP1CC.
   
  
 0.648
C12orf40
Uncharacterized protein C12orf40; Chromosome 12 open reading frame 40.
   
  
 0.637
C9orf43
Uncharacterized protein C9orf43; Chromosome 9 open reading frame 43.
   
  
 0.616
TEX33
Testis-expressed protein 33; Testis expressed 33.
   
  
 0.614
SPATA16
Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion.
   
  
 0.598
TMCO2
Transmembrane and coiled-coil domains 2.
   
  
 0.597
C9orf131
Uncharacterized protein C9orf131; Chromosome 9 open reading frame 131.
   
  
 0.590
C20orf173
Uncharacterized protein C20orf173; Chromosome 20 open reading frame 173.
   
  
 0.579
MAGEB16
Melanoma-associated antigen B16; MAGE family member B16.
      
 0.566
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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