node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C2CD6 | C7orf61 | ENSP00000409937 | ENSP00000327732 | C2 calcium-dependent domain-containing protein 6; C2 calcium dependent domain containing 6. | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | 0.678 |
C2CD6 | CCDC62 | ENSP00000409937 | ENSP00000253079 | C2 calcium-dependent domain-containing protein 6; C2 calcium dependent domain containing 6. | Coiled-coil domain-containing protein 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. | 0.507 |
C2CD6 | DNAH17 | ENSP00000409937 | ENSP00000374490 | C2 calcium-dependent domain-containing protein 6; C2 calcium dependent domain containing 6. | Dynein heavy chain 17, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). | 0.457 |
C2CD6 | DPY19L2 | ENSP00000409937 | ENSP00000315988 | C2 calcium-dependent domain-containing protein 6; C2 calcium dependent domain containing 6. | Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family. | 0.468 |
C2CD6 | SPATA16 | ENSP00000409937 | ENSP00000341765 | C2 calcium-dependent domain-containing protein 6; C2 calcium dependent domain containing 6. | Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion. | 0.596 |
C2CD6 | ZPBP | ENSP00000409937 | ENSP00000046087 | C2 calcium-dependent domain-containing protein 6; C2 calcium dependent domain containing 6. | Zona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization (By similarity). | 0.488 |
C7orf61 | C2CD6 | ENSP00000327732 | ENSP00000409937 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | C2 calcium-dependent domain-containing protein 6; C2 calcium dependent domain containing 6. | 0.678 |
C7orf61 | CCDC62 | ENSP00000327732 | ENSP00000253079 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | Coiled-coil domain-containing protein 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. | 0.539 |
C7orf61 | DNAH17 | ENSP00000327732 | ENSP00000374490 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | Dynein heavy chain 17, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). | 0.540 |
C7orf61 | DPY19L2 | ENSP00000327732 | ENSP00000315988 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family. | 0.635 |
C7orf61 | PILRB | ENSP00000327732 | ENSP00000391748 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | Paired immunoglobulin-like type 2 receptor beta; Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface. | 0.474 |
C7orf61 | PPP1R35 | ENSP00000327732 | ENSP00000292330 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | Protein phosphatase 1 regulatory subunit 35; Inhibits PPP1CA phosphatase activity. Belongs to the PPP1R35 family. | 0.571 |
C7orf61 | SPATA16 | ENSP00000327732 | ENSP00000341765 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion. | 0.679 |
C7orf61 | TSC22D4 | ENSP00000327732 | ENSP00000300181 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | TSC22 domain family protein 4; Transcriptional repressor. | 0.926 |
C7orf61 | ZCWPW1 | ENSP00000327732 | ENSP00000381109 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | Zinc finger CW-type and PWWP domain containing 1. | 0.455 |
C7orf61 | ZPBP | ENSP00000327732 | ENSP00000046087 | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | Zona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization (By similarity). | 0.647 |
CCDC62 | C2CD6 | ENSP00000253079 | ENSP00000409937 | Coiled-coil domain-containing protein 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. | C2 calcium-dependent domain-containing protein 6; C2 calcium dependent domain containing 6. | 0.507 |
CCDC62 | C7orf61 | ENSP00000253079 | ENSP00000327732 | Coiled-coil domain-containing protein 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. | Uncharacterized protein C7orf61; Chromosome 7 open reading frame 61. | 0.539 |
CCDC62 | DPY19L2 | ENSP00000253079 | ENSP00000315988 | Coiled-coil domain-containing protein 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. | Probable C-mannosyltransferase DPY19L2; Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins (By similarity). Required during spermatogenesis for sperm head elongation and acrosome formation; Belongs to the dpy-19 family. | 0.596 |
CCDC62 | SPATA16 | ENSP00000253079 | ENSP00000341765 | Coiled-coil domain-containing protein 62; Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. | Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion. | 0.581 |