STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH2D7SH2 domain containing 7. (451 aa)    
Predicted Functional Partners:
C3orf22
Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.
      
 0.596
C12orf56
Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.
      
 0.571
RNASE12
Probable inactive ribonuclease-like protein 12; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family.
      
 0.571
SMIM17
Small integral membrane protein 17.
      
 0.543
TMEM45B
Transmembrane protein 45B.
      
 0.542
LRMP
Processed lymphoid-restricted membrane protein; Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion.
      
 0.519
TSPAN6
Tetraspanin-6; Tetraspanin 6.
      
 0.513
CC2D2B
Protein CC2D2B; Coiled-coil and C2 domain containing 2B.
      
 0.508
C22orf42
Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.
      
 0.507
C1orf167
Uncharacterized protein C1orf167; Chromosome 1 open reading frame 167.
      
 0.507
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.