SH2D7 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AVIL	SH2D7	ENSP00000257861	ENSP00000327846	Advillin; Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.	SH2 domain containing 7.	0.493
C12orf56	C3orf22	ENSP00000446101	ENSP00000316644	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	0.570
C12orf56	SH2D7	ENSP00000446101	ENSP00000327846	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	SH2 domain containing 7.	0.500
C12orf56	SMIM17	ENSP00000446101	ENSP00000471126	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Small integral membrane protein 17.	0.536
C3orf22	C12orf56	ENSP00000316644	ENSP00000446101	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	0.570
C3orf22	SH2D7	ENSP00000316644	ENSP00000327846	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	SH2 domain containing 7.	0.549
C3orf22	SMIM17	ENSP00000316644	ENSP00000471126	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	Small integral membrane protein 17.	0.694
ERICH4	RPRML	ENSP00000367429	ENSP00000318032	Glutamate-rich protein 4; Glutamate rich 4.	Reprimo-like protein; Reprimo like.	0.553
ERICH4	SH2D7	ENSP00000367429	ENSP00000327846	Glutamate-rich protein 4; Glutamate rich 4.	SH2 domain containing 7.	0.668
GNG13	SH2D7	ENSP00000248150	ENSP00000327846	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	SH2 domain containing 7.	0.607
LRMP	SH2D6	ENSP00000346442	ENSP00000498488	Processed lymphoid-restricted membrane protein; Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion.	SH2 domain containing 6.	0.420
LRMP	SH2D7	ENSP00000346442	ENSP00000327846	Processed lymphoid-restricted membrane protein; Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion.	SH2 domain containing 7.	0.605
RPRML	ERICH4	ENSP00000318032	ENSP00000367429	Reprimo-like protein; Reprimo like.	Glutamate-rich protein 4; Glutamate rich 4.	0.553
RPRML	SH2D7	ENSP00000318032	ENSP00000327846	Reprimo-like protein; Reprimo like.	SH2 domain containing 7.	0.578
SH2D6	LRMP	ENSP00000498488	ENSP00000346442	SH2 domain containing 6.	Processed lymphoid-restricted membrane protein; Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules; this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion.	0.420
SH2D6	SH2D7	ENSP00000498488	ENSP00000327846	SH2 domain containing 6.	SH2 domain containing 7.	0.488
SH2D7	AVIL	ENSP00000327846	ENSP00000257861	SH2 domain containing 7.	Advillin; Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.	0.493
SH2D7	C12orf56	ENSP00000327846	ENSP00000446101	SH2 domain containing 7.	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	0.500
SH2D7	C3orf22	ENSP00000327846	ENSP00000316644	SH2 domain containing 7.	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	0.549
SH2D7	ERICH4	ENSP00000327846	ENSP00000367429	SH2 domain containing 7.	Glutamate-rich protein 4; Glutamate rich 4.	0.668