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SLC5A2 protein (human) - STRING interaction network
"SLC5A2" - Sodium/glucose cotransporter 2 in Homo sapiens
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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SLC5A2Sodium/glucose cotransporter 2; Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1-1; Solute carriers (672 aa)    
Predicted Functional Partners:
DPP4
Dipeptidyl peptidase 4; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF- kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and in [...] (766 aa)
           
  0.892
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (110 aa)
           
  0.873
REG1A
Lithostathine-1-alpha; Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration; C-type lectin domain containing (166 aa)
           
  0.868
ADCY7
Adenylate cyclase type 7; This is a membrane-bound, calcium-inhibitable adenylyl cyclase; Adenylate cyclases (1080 aa)
           
  0.808
SLC6A2
Sodium-dependent noradrenaline transporter; Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals; Belongs to the sodium-neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A2 subfamily (628 aa)
           
  0.804
GCG
Glucagon; Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life; Belongs to the glucagon family (180 aa)
           
  0.796
GLP1R
Glucagon-like peptide 1 receptor; G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1 (By similarity) (463 aa)
           
  0.729
SLC6A18
Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter; Belongs to the sodium-neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A18 subfamily (628 aa)
     
   
  0.722
ILVBL
Acetolactate synthase-like protein; ilvB acetolactate synthase like (632 aa)
         
  0.720
SLC13A3
Solute carrier family 13 member 3; High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate; Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily (602 aa)
     
   
  0.717
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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