SPEM2 protein (human) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

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Score

SPEM2

Uncharacterized protein SPEM2; SPEM family member 2. (501 aa)

Predicted Functional Partners:

SPEM3

0.684

C17orf50

0.675

TLDC2

0.607

C17orf98

0.584

CFAP97D1

0.580

LEXM

0.527

TSSK6

0.468

KRTAP9-7

0.418

TBC1D3K

0.418

SPEM1

0.414

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C17orf50	C17orf98	ENSP00000475146	ENSP00000479396	Uncharacterized protein C17orf50; Chromosome 17 open reading frame 50.	Uncharacterized protein C17orf98; Chromosome 17 open reading frame 98.	0.695
C17orf50	CFAP97D1	ENSP00000475146	ENSP00000415662	Uncharacterized protein C17orf50; Chromosome 17 open reading frame 50.	Uncharacterized protein CFAP97D1; CFAP97 domain containing 1; Belongs to the CFAP97 family.	0.691
C17orf50	KRTAP9-7	ENSP00000475146	ENSP00000375149	Uncharacterized protein C17orf50; Chromosome 17 open reading frame 50.	Keratin-associated protein 9-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family.	0.545
C17orf50	SPEM2	ENSP00000475146	ENSP00000328061	Uncharacterized protein C17orf50; Chromosome 17 open reading frame 50.	Uncharacterized protein SPEM2; SPEM family member 2.	0.675
C17orf50	TBC1D3K	ENSP00000475146	ENSP00000484181	Uncharacterized protein C17orf50; Chromosome 17 open reading frame 50.	TBC1 domain family member 3K; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).	0.570
C17orf98	C17orf50	ENSP00000479396	ENSP00000475146	Uncharacterized protein C17orf98; Chromosome 17 open reading frame 98.	Uncharacterized protein C17orf50; Chromosome 17 open reading frame 50.	0.695
C17orf98	CFAP97D1	ENSP00000479396	ENSP00000415662	Uncharacterized protein C17orf98; Chromosome 17 open reading frame 98.	Uncharacterized protein CFAP97D1; CFAP97 domain containing 1; Belongs to the CFAP97 family.	0.582
C17orf98	KRTAP9-7	ENSP00000479396	ENSP00000375149	Uncharacterized protein C17orf98; Chromosome 17 open reading frame 98.	Keratin-associated protein 9-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family.	0.433
C17orf98	SPEM2	ENSP00000479396	ENSP00000328061	Uncharacterized protein C17orf98; Chromosome 17 open reading frame 98.	Uncharacterized protein SPEM2; SPEM family member 2.	0.584
C17orf98	TBC1D3K	ENSP00000479396	ENSP00000484181	Uncharacterized protein C17orf98; Chromosome 17 open reading frame 98.	TBC1 domain family member 3K; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).	0.434
CFAP97D1	C17orf50	ENSP00000415662	ENSP00000475146	Uncharacterized protein CFAP97D1; CFAP97 domain containing 1; Belongs to the CFAP97 family.	Uncharacterized protein C17orf50; Chromosome 17 open reading frame 50.	0.691
CFAP97D1	C17orf98	ENSP00000415662	ENSP00000479396	Uncharacterized protein CFAP97D1; CFAP97 domain containing 1; Belongs to the CFAP97 family.	Uncharacterized protein C17orf98; Chromosome 17 open reading frame 98.	0.582
CFAP97D1	KRTAP9-7	ENSP00000415662	ENSP00000375149	Uncharacterized protein CFAP97D1; CFAP97 domain containing 1; Belongs to the CFAP97 family.	Keratin-associated protein 9-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family.	0.448
CFAP97D1	SPEM2	ENSP00000415662	ENSP00000328061	Uncharacterized protein CFAP97D1; CFAP97 domain containing 1; Belongs to the CFAP97 family.	Uncharacterized protein SPEM2; SPEM family member 2.	0.580
CFAP97D1	TBC1D3K	ENSP00000415662	ENSP00000484181	Uncharacterized protein CFAP97D1; CFAP97 domain containing 1; Belongs to the CFAP97 family.	TBC1 domain family member 3K; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).	0.446
KRTAP9-7	C17orf50	ENSP00000375149	ENSP00000475146	Keratin-associated protein 9-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family.	Uncharacterized protein C17orf50; Chromosome 17 open reading frame 50.	0.545
KRTAP9-7	C17orf98	ENSP00000375149	ENSP00000479396	Keratin-associated protein 9-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family.	Uncharacterized protein C17orf98; Chromosome 17 open reading frame 98.	0.433
KRTAP9-7	CFAP97D1	ENSP00000375149	ENSP00000415662	Keratin-associated protein 9-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family.	Uncharacterized protein CFAP97D1; CFAP97 domain containing 1; Belongs to the CFAP97 family.	0.448
KRTAP9-7	SPEM2	ENSP00000375149	ENSP00000328061	Keratin-associated protein 9-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family.	Uncharacterized protein SPEM2; SPEM family member 2.	0.418
KRTAP9-7	TBC1D3K	ENSP00000375149	ENSP00000484181	Keratin-associated protein 9-7; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family.	TBC1 domain family member 3K; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).	0.526