STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM47BProtein FAM47B; Family with sequence similarity 47 member B; Belongs to the FAM47 family. (645 aa)    
Predicted Functional Partners:
SATL1
Spermidine/spermine N1-acetyl transferase like 1.
    
 
 0.609
TMEM47
Transmembrane protein 47; Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin (By similarity); Belongs to the TMEM47 family.
      
 0.581
TMEM191B
Transmembrane protein 191B.
      
 0.576
MAP7D3
MAP7 domain-containing protein 3; Promotes the assembly and stability of microtubules.
    
 
 0.556
CFAP47
Cilia and flagella associated protein 47.
   
  
 0.532
OR13C8
Olfactory receptor 13C8; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.529
PLGLB2
Plasminogen like B2.
    
 
 0.512
MAP3K15
Mitogen-activated protein kinase kinase kinase 15; May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis.
   
 
 0.510
ARSF
Arylsulfatase F.
      
 0.505
SAGE1
Sarcoma antigen 1.
  
  
 0.498
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.