node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHID1 | EFHC1 | ENSP00000398722 | ENSP00000360107 | Chitinase domain-containing protein 1; Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro); Belongs to the glycosyl hydrolase 18 family. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.512 |
CHID1 | VMO1 | ENSP00000398722 | ENSP00000328397 | Chitinase domain-containing protein 1; Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro); Belongs to the glycosyl hydrolase 18 family. | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | 0.417 |
EFHC1 | CHID1 | ENSP00000360107 | ENSP00000398722 | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | Chitinase domain-containing protein 1; Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro); Belongs to the glycosyl hydrolase 18 family. | 0.512 |
EFHC1 | SPEF1 | ENSP00000360107 | ENSP00000369080 | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | Sperm flagellar protein 1; Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation. Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity). Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock (By similarity). | 0.487 |
EFHC1 | VMO1 | ENSP00000360107 | ENSP00000328397 | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | 0.508 |
SPEF1 | EFHC1 | ENSP00000369080 | ENSP00000360107 | Sperm flagellar protein 1; Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation. Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity). Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock (By similarity). | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.487 |
SPEF1 | VMO1 | ENSP00000369080 | ENSP00000328397 | Sperm flagellar protein 1; Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation. Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity). Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock (By similarity). | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | 0.460 |
STYXL1 | VMO1 | ENSP00000248600 | ENSP00000328397 | Serine/threonine/tyrosine-interacting-like protein 1; Catalytically inactive phosphatase. By binding to G3BP1, inhibits the formation of G3BP1- induced stress granules. Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149'. Inhibits PTPMT1 phosphatase activity. By inhibiting PTPMT1, positively regulates intrinsic apoptosis. May play a role in the formation of neurites during neuronal development. Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | 0.409 |
TMEM200A | VMO1 | ENSP00000376224 | ENSP00000328397 | Transmembrane protein 200A; Belongs to the TMEM200 family. | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | 0.465 |
TMEM252 | VMO1 | ENSP00000366528 | ENSP00000328397 | Transmembrane protein 252. | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | 0.420 |
VMO1 | CHID1 | ENSP00000328397 | ENSP00000398722 | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | Chitinase domain-containing protein 1; Saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro); Belongs to the glycosyl hydrolase 18 family. | 0.417 |
VMO1 | EFHC1 | ENSP00000328397 | ENSP00000360107 | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | EF-hand domain-containing protein 1; Microtubule-associated protein which regulates cell division and neuronal migration during cortical development. Necessary for mitotic spindle organization. Necessary for radial and tangential cell migration during brain development, possibly acting as a regulator of cell morphology and process formation during migration. May enhance calcium influx through CACNA1E and stimulate programmed cell death. | 0.508 |
VMO1 | SPEF1 | ENSP00000328397 | ENSP00000369080 | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | Sperm flagellar protein 1; Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation. Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity). Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock (By similarity). | 0.460 |
VMO1 | STYXL1 | ENSP00000328397 | ENSP00000248600 | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | Serine/threonine/tyrosine-interacting-like protein 1; Catalytically inactive phosphatase. By binding to G3BP1, inhibits the formation of G3BP1- induced stress granules. Does not act by protecting the dephosphorylation of G3BP1 at 'Ser-149'. Inhibits PTPMT1 phosphatase activity. By inhibiting PTPMT1, positively regulates intrinsic apoptosis. May play a role in the formation of neurites during neuronal development. Belongs to the protein-tyrosine phosphatase family. Non- receptor class subfamily. | 0.409 |
VMO1 | TMEM200A | ENSP00000328397 | ENSP00000376224 | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | Transmembrane protein 200A; Belongs to the TMEM200 family. | 0.465 |
VMO1 | TMEM252 | ENSP00000328397 | ENSP00000366528 | Vitelline membrane outer layer 1 homolog; Belongs to the VMO1 family. | Transmembrane protein 252. | 0.420 |