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KANK3 protein (human) - STRING interaction network
"KANK3" - KN motif and ankyrin repeat domain-containing protein 3 in Homo sapiens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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KANK3KN motif and ankyrin repeat domain-containing protein 3; May be involved in the control of cytoskeleton formation by regulating actin polymerization; Ankyrin repeat domain containing (821 aa)    
Predicted Functional Partners:
CCDC73
Coiled-coil domain containing 73 (1079 aa)
           
  0.742
RPS28
Ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family (69 aa)
           
  0.643
PHLDA3
Pleckstrin homology-like domain family A member 3; p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor; Belongs to the PHLDA3 family (127 aa)
     
   
  0.593
PRRG3
Transmembrane gamma-carboxyglutamic acid protein 3; Proline rich and Gla domain containing (231 aa)
           
  0.589
ANGPTL4
Angiopoietin-related protein 4; Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associa [...] (406 aa)
     
 
  0.571
CRIP2
Cysteine rich protein 2; LIM domain containing (282 aa)
     
 
  0.565
RFX7
DNA-binding protein RFX7; Regulatory factor X family; Belongs to the RFX family (1363 aa)
       
 
  0.552
BPTF
Nucleosome-remodeling factor subunit BPTF; Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on ’Lys-4’ (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors; Belongs to the PBTF family (2920 aa)
     
 
  0.543
KCNV2
Potassium voltage-gated channel subfamily V member 2; Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values; Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.2/KCNV2 sub-subfamily (545 aa)
           
  0.540
ABHD4
Protein ABHD4; Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethan [...] (342 aa)
       
 
  0.537
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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