STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRT36Keratin, type I cuticular Ha6; Keratin 36; Belongs to the intermediate filament family. (467 aa)    
Predicted Functional Partners:
NAIF1
Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.
   
 
 0.625
KRT84
Keratin, type II cuticular Hb4; Keratin 84.
  
  
0.609
EXOC8
Exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane; Belongs to the EXO84 family.
    
   0.591
KRTAP3-1
Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
   
  
 0.550
KRT33B
Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family.
  
 
0.528
KRT33A
Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family.
  
 
0.509
KRT35
Keratin, type I cuticular Ha5; Keratin 35; Belongs to the intermediate filament family.
  
 
0.499
KRT38
Keratin, type I cuticular Ha8; Keratin 38; Belongs to the intermediate filament family.
  
 
0.497
KRT27
Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs).
  
 
0.494
KRT26
Keratin, type I cytoskeletal 26; Keratin 26.
  
 
0.488
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.