ODF3L1 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C11orf1	C1orf100	ENSP00000260276	ENSP00000311218	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	0.832
C11orf1	C7orf31	ENSP00000260276	ENSP00000283905	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.872
C11orf1	CATIP	ENSP00000260276	ENSP00000289388	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	0.632
C11orf1	DNAH10	ENSP00000260276	ENSP00000489675	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	0.640
C11orf1	EFCAB6	ENSP00000260276	ENSP00000262726	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.	0.852
C11orf1	GAS8	ENSP00000260276	ENSP00000268699	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Dynein regulatory complex subunit 4; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh [...]	0.818
C11orf1	ODF3B	ENSP00000260276	ENSP00000382804	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Outer dense fiber of sperm tails 3B.	0.832
C11orf1	ODF3L1	ENSP00000260276	ENSP00000329584	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Outer dense fiber of sperm tails 3 like 1; Belongs to the ODF3 family.	0.632
C11orf1	ROPN1L	ENSP00000260276	ENSP00000421405	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.	0.818
C1orf100	C11orf1	ENSP00000311218	ENSP00000260276	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	0.832
C1orf100	C7orf31	ENSP00000311218	ENSP00000283905	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.832
C1orf100	CATIP	ENSP00000311218	ENSP00000289388	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization.	0.632
C1orf100	DNAH10	ENSP00000311218	ENSP00000489675	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	Dynein heavy chain 10, axonemal; Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). Probable inner arm dynein heavy chain.	0.632
C1orf100	EFCAB6	ENSP00000311218	ENSP00000262726	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.	0.832
C1orf100	GAS8	ENSP00000311218	ENSP00000268699	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	Dynein regulatory complex subunit 4; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays an important role in the assembly of the N-DRC linker (By similarity). Plays dual roles at both the primary (or non-motile) cilia to regulate hedgehog signaling and in motile cilia to coordinate cilia movement. Required for proper motile cilia functioning. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh [...]	0.632
C1orf100	ODF3B	ENSP00000311218	ENSP00000382804	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	Outer dense fiber of sperm tails 3B.	0.832
C1orf100	ODF3L1	ENSP00000311218	ENSP00000329584	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	Outer dense fiber of sperm tails 3 like 1; Belongs to the ODF3 family.	0.632
C1orf100	ROPN1L	ENSP00000311218	ENSP00000421405	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation.	0.632
C7orf31	C11orf1	ENSP00000283905	ENSP00000260276	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.	0.872
C7orf31	C1orf100	ENSP00000283905	ENSP00000311218	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Uncharacterized protein C1orf100; Chromosome 1 open reading frame 100.	0.832