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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPATA31A6Spermatogenesis-associated protein 31A6; May play a role in spermatogenesis; Belongs to the SPATA31 family. (1343 aa)    
Predicted Functional Partners:
SMKR1
Small lysine rich protein 1.
      
 0.608
ANKRD20A4
Ankyrin repeat domain-containing protein 20A4.
      
 0.601
ZNF705G
Putative zinc finger protein 705G; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.599
DCAF8L2
DDB1- and CUL4-associated factor 8-like protein 2; DDB1 and CUL4 associated factor 8 like 2; Belongs to the WD repeat DCAF8 family.
      
 0.544
KLRG2
Killer cell lectin like receptor G2.
      
 0.474
SPNS3
Protein spinster homolog 3; Sphingolipid transporter.
      
 0.457
C11orf80
Type 2 DNA topoisomerase 6 subunit B-like; [Isoform 3]: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles.
      
 0.436
WSCD2
WSC domain containing 2; Belongs to the WSCD family.
      
 0.435
PPP4R3C
Protein phosphatase 4 regulatory subunit 3C.
      
 0.416
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.