STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM186AProtein FAM186A; Family with sequence similarity 186 member A; Belongs to the FAM186 family. (2351 aa)    
Predicted Functional Partners:
FAM47C
Putative protein FAM47C; Family with sequence similarity 47 member C; Belongs to the FAM47 family.
   
 
 0.573
GOLGA6L2
Golgin subfamily A member 6-like protein 2; Golgin A6 family like 2; Belongs to the GOLGA6 family.
   
 
 0.517
FAM170B
Protein FAM170B; Plays a role in fertilization through the acrosome reaction. Belongs to the FAM170 family.
   
 
 0.475
FER1L6
Fer-1-like protein 6; Fer-1 like family member 6.
      
 0.447
TMPRSS15
Enteropeptidase non-catalytic heavy chain; Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
   
 
 0.435
ZNF850
Zinc finger protein 850; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
   
 
 0.434
UTP23
rRNA-processing protein UTP23 homolog; Involved in rRNA-processing and ribosome biogenesis. Belongs to the UTP23/FCF1 family. UTP23 subfamily.
    
 
 0.433
OR2T4
Olfactory receptor 2T4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.420
EFCAB5
EF-hand calcium-binding domain-containing protein 5; EF-hand calcium binding domain 5.
   
 
 0.409
DIP2B
Disco interacting protein 2 homolog B.
    
 
 0.408
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.