CYLC1 protein (human) - STRING interaction network

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Score

CYLC1

Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation. (651 aa)

Predicted Functional Partners:

CCIN

0.982

CYLC2

0.663

CPXCR1

0.652

SATL1

0.583

APOOL

0.579

CCNL1

0.578

RPS6KA6

0.565

PCDH11X

0.528

TENT5D

0.526

BRWD3

0.525

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOOL	BRWD3	ENSP00000362268	ENSP00000362372	MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.	Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	0.465
APOOL	CPXCR1	ENSP00000362268	ENSP00000276127	MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.	CPX chromosome region candidate 1.	0.418
APOOL	CYLC1	ENSP00000362268	ENSP00000331556	MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	0.579
APOOL	RPS6KA6	ENSP00000362268	ENSP00000262752	MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.	Ribosomal protein S6 kinase alpha-6; Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.	0.555
APOOL	SATL1	ENSP00000362268	ENSP00000425421	MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.	Spermidine/spermine N1-acetyl transferase like 1.	0.613
APOOL	TENT5D	ENSP00000362268	ENSP00000443410	MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.	Terminal nucleotidyltransferase 5D; Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase; Belongs to the TENT family.	0.416
BRWD3	APOOL	ENSP00000362372	ENSP00000362268	Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.	0.465
BRWD3	CYLC1	ENSP00000362372	ENSP00000331556	Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	0.525
BRWD3	RPS6KA6	ENSP00000362372	ENSP00000262752	Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	Ribosomal protein S6 kinase alpha-6; Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.	0.422
BRWD3	SATL1	ENSP00000362372	ENSP00000425421	Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	Spermidine/spermine N1-acetyl transferase like 1.	0.421
BRWD3	TENT5D	ENSP00000362372	ENSP00000443410	Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	Terminal nucleotidyltransferase 5D; Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase; Belongs to the TENT family.	0.483
CCIN	CYLC1	ENSP00000334996	ENSP00000331556	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation.	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	0.982
CCIN	CYLC2	ENSP00000334996	ENSP00000420256	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation.	Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	0.989
CCNL1	CYLC1	ENSP00000295926	ENSP00000331556	Cyclin-L1; Involved in pre-mRNA splicing. Functions in association with cyclin-dependent kinases (CDKs). Inhibited by the CDK-specific inhibitor CDKN1A/p21. May play a role in the regulation of RNA polymerase II (pol II). May be a candidate proto- oncogene in head and neck squamous cell carcinomas (HNSCC).	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	0.578
CPXCR1	APOOL	ENSP00000276127	ENSP00000362268	CPX chromosome region candidate 1.	MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.	0.418
CPXCR1	CYLC1	ENSP00000276127	ENSP00000331556	CPX chromosome region candidate 1.	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	0.652
CPXCR1	SATL1	ENSP00000276127	ENSP00000425421	CPX chromosome region candidate 1.	Spermidine/spermine N1-acetyl transferase like 1.	0.583
CYLC1	APOOL	ENSP00000331556	ENSP00000362268	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function.	0.579
CYLC1	BRWD3	ENSP00000331556	ENSP00000362372	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	Bromodomain and WD repeat-containing protein 3; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.	0.525
CYLC1	CCIN	ENSP00000331556	ENSP00000334996	Cylicin-1; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation.	Calicin; Possible morphogenetic cytoskeletal element in spermiogenic differentiation.	0.982