C11orf87 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGAP20	C11orf53	ENSP00000260283	ENSP00000489630	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.	Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53.	0.442
ARHGAP20	C11orf87	ENSP00000260283	ENSP00000331581	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	0.431
C11orf53	ARHGAP20	ENSP00000489630	ENSP00000260283	Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53.	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.	0.442
C11orf53	C11orf87	ENSP00000489630	ENSP00000331581	Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53.	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	0.432
C11orf53	COLCA2	ENSP00000489630	ENSP00000484135	Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53.	Colorectal cancer associated 2.	0.863
C11orf87	ARHGAP20	ENSP00000331581	ENSP00000260283	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	Rho GTPase-activating protein 20; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.	0.431
C11orf87	C11orf53	ENSP00000331581	ENSP00000489630	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53.	0.432
C11orf87	COLCA2	ENSP00000331581	ENSP00000484135	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	Colorectal cancer associated 2.	0.415
C11orf87	FREM3	ENSP00000331581	ENSP00000332886	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	FRAS1-related extracellular matrix protein 3; Extracellular matrix protein which may play a role in cell adhesion.	0.406
C11orf87	NETO2	ENSP00000331581	ENSP00000455169	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	Neuropilin and tolloid-like protein 2; Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission (By similarity).	0.465
C11orf87	SERPINA11	ENSP00000331581	ENSP00000335024	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	Serpin family A member 11.	0.465
C11orf87	SERPINA9	ENSP00000331581	ENSP00000337133	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	Serpin A9; Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro).	0.436
C11orf87	SLC15A2	ENSP00000331581	ENSP00000417085	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	Solute carrier family 15 member 2; Proton-coupled intake of oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports the dipeptide-like aminopeptidase inhibitor bestatin (By similarity). Can also transport the aminocephalosporin antibiotic cefadroxil (By similarity); Belongs to the PTR2/POT transporter (TC 2.A.17) family.	0.536
C11orf87	SRPK1	ENSP00000331581	ENSP00000362931	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	SRSF protein kinase 1; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Can influence additional steps of mRNA maturation, as well as other cellular activiti [...]	0.457
C11orf87	TMEM17	ENSP00000331581	ENSP00000335094	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity); Belongs to the TMEM17 family.	0.449
COLCA2	C11orf53	ENSP00000484135	ENSP00000489630	Colorectal cancer associated 2.	Uncharacterized protein C11orf53; Chromosome 11 open reading frame 53.	0.863
COLCA2	C11orf87	ENSP00000484135	ENSP00000331581	Colorectal cancer associated 2.	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	0.415
FREM3	C11orf87	ENSP00000332886	ENSP00000331581	FRAS1-related extracellular matrix protein 3; Extracellular matrix protein which may play a role in cell adhesion.	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	0.406
NETO2	C11orf87	ENSP00000455169	ENSP00000331581	Neuropilin and tolloid-like protein 2; Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission (By similarity).	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	0.465
SERPINA11	C11orf87	ENSP00000335024	ENSP00000331581	Serpin family A member 11.	Uncharacterized protein C11orf87; Chromosome 11 open reading frame 87.	0.465