Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but at higher resolution
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDH22 | WSCD2 | ENSP00000437790 | ENSP00000448047 | Cadherin-22; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues (By similarity). | WSC domain containing 2; Belongs to the WSCD family. | 0.404 |
DKK1 | WSCD2 | ENSP00000363081 | ENSP00000448047 | Dickkopf-related protein 1; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner [...] | WSC domain containing 2; Belongs to the WSCD family. | 0.413 |
FANCM | WSCD2 | ENSP00000267430 | ENSP00000448047 | Fanconi anemia group M protein; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross- linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork- structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. This acti [...] | WSC domain containing 2; Belongs to the WSCD family. | 0.879 |
LRP2BP | WSCD2 | ENSP00000332681 | ENSP00000448047 | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | WSC domain containing 2; Belongs to the WSCD family. | 0.417 |
SGSM1 | WSCD2 | ENSP00000383212 | ENSP00000448047 | Small G protein signaling modulator 1; Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B; Belongs to the RUTBC family. | WSC domain containing 2; Belongs to the WSCD family. | 0.468 |
SPATA31A6 | WSCD2 | ENSP00000329825 | ENSP00000448047 | Spermatogenesis-associated protein 31A6; May play a role in spermatogenesis; Belongs to the SPATA31 family. | WSC domain containing 2; Belongs to the WSCD family. | 0.435 |
WSCD2 | CDH22 | ENSP00000448047 | ENSP00000437790 | WSC domain containing 2; Belongs to the WSCD family. | Cadherin-22; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues (By similarity). | 0.404 |
WSCD2 | DKK1 | ENSP00000448047 | ENSP00000363081 | WSC domain containing 2; Belongs to the WSCD family. | Dickkopf-related protein 1; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner [...] | 0.413 |
WSCD2 | FANCM | ENSP00000448047 | ENSP00000267430 | WSC domain containing 2; Belongs to the WSCD family. | Fanconi anemia group M protein; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross- linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork- structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. This acti [...] | 0.879 |
WSCD2 | LRP2BP | ENSP00000448047 | ENSP00000332681 | WSC domain containing 2; Belongs to the WSCD family. | LRP2-binding protein; May act as an adapter that regulates LRP2 function. | 0.417 |
WSCD2 | SGSM1 | ENSP00000448047 | ENSP00000383212 | WSC domain containing 2; Belongs to the WSCD family. | Small G protein signaling modulator 1; Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B; Belongs to the RUTBC family. | 0.468 |
WSCD2 | SPATA31A6 | ENSP00000448047 | ENSP00000329825 | WSC domain containing 2; Belongs to the WSCD family. | Spermatogenesis-associated protein 31A6; May play a role in spermatogenesis; Belongs to the SPATA31 family. | 0.435 |