MBD3L3 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Export your current network:

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file format is 'PNG': portable network graphic

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUXA	H3Y1	ENSP00000452398	ENSP00000496014	Double homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family.	Histone H3.Y; Primate-specific variant histone H3, which constitutes a core component of nucleosomes. Histone H3.Y-containing nucleosomes accumulate around transcription start sites and have flexible DNA ends, suggesting that they form relaxed chromatin that allows transcription factor access. Histone H1 binds less efficiently to histone H3.Y-containing nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl [...]	0.449
DUXA	LEUTX	ENSP00000452398	ENSP00000380053	Double homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family.	Leucine twenty homeobox.	0.749
DUXA	MBD3L2	ENSP00000452398	ENSP00000370800	Double homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family.	methyl-CpG binding domain protein 3 like 2; Belongs to the MBD3L family.	0.516
DUXA	MBD3L3	ENSP00000452398	ENSP00000333183	Double homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family.	methyl-CpG binding domain protein 3 like 3.	0.586
DUXA	MBD3L5	ENSP00000452398	ENSP00000331435	Double homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family.	methyl-CpG binding domain protein 3 like 5.	0.457
DUXA	PRAMEF15	ENSP00000452398	ENSP00000365322	Double homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family.	PRAME family member 15; Belongs to the PRAME family.	0.408
DUXB	H3Y1	ENSP00000491301	ENSP00000496014	Double homeobox B.	Histone H3.Y; Primate-specific variant histone H3, which constitutes a core component of nucleosomes. Histone H3.Y-containing nucleosomes accumulate around transcription start sites and have flexible DNA ends, suggesting that they form relaxed chromatin that allows transcription factor access. Histone H1 binds less efficiently to histone H3.Y-containing nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl [...]	0.422
DUXB	LEUTX	ENSP00000491301	ENSP00000380053	Double homeobox B.	Leucine twenty homeobox.	0.757
DUXB	MBD3L2	ENSP00000491301	ENSP00000370800	Double homeobox B.	methyl-CpG binding domain protein 3 like 2; Belongs to the MBD3L family.	0.549
DUXB	MBD3L3	ENSP00000491301	ENSP00000333183	Double homeobox B.	methyl-CpG binding domain protein 3 like 3.	0.547
DUXB	MBD3L5	ENSP00000491301	ENSP00000331435	Double homeobox B.	methyl-CpG binding domain protein 3 like 5.	0.499
H3Y1	DUXA	ENSP00000496014	ENSP00000452398	Histone H3.Y; Primate-specific variant histone H3, which constitutes a core component of nucleosomes. Histone H3.Y-containing nucleosomes accumulate around transcription start sites and have flexible DNA ends, suggesting that they form relaxed chromatin that allows transcription factor access. Histone H1 binds less efficiently to histone H3.Y-containing nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl [...]	Double homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family.	0.449
H3Y1	DUXB	ENSP00000496014	ENSP00000491301	Histone H3.Y; Primate-specific variant histone H3, which constitutes a core component of nucleosomes. Histone H3.Y-containing nucleosomes accumulate around transcription start sites and have flexible DNA ends, suggesting that they form relaxed chromatin that allows transcription factor access. Histone H1 binds less efficiently to histone H3.Y-containing nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl [...]	Double homeobox B.	0.422
H3Y1	LEUTX	ENSP00000496014	ENSP00000380053	Histone H3.Y; Primate-specific variant histone H3, which constitutes a core component of nucleosomes. Histone H3.Y-containing nucleosomes accumulate around transcription start sites and have flexible DNA ends, suggesting that they form relaxed chromatin that allows transcription factor access. Histone H1 binds less efficiently to histone H3.Y-containing nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl [...]	Leucine twenty homeobox.	0.470
H3Y1	MBD3L3	ENSP00000496014	ENSP00000333183	Histone H3.Y; Primate-specific variant histone H3, which constitutes a core component of nucleosomes. Histone H3.Y-containing nucleosomes accumulate around transcription start sites and have flexible DNA ends, suggesting that they form relaxed chromatin that allows transcription factor access. Histone H1 binds less efficiently to histone H3.Y-containing nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl [...]	methyl-CpG binding domain protein 3 like 3.	0.528
H3Y1	MBD3L5	ENSP00000496014	ENSP00000331435	Histone H3.Y; Primate-specific variant histone H3, which constitutes a core component of nucleosomes. Histone H3.Y-containing nucleosomes accumulate around transcription start sites and have flexible DNA ends, suggesting that they form relaxed chromatin that allows transcription factor access. Histone H1 binds less efficiently to histone H3.Y-containing nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl [...]	methyl-CpG binding domain protein 3 like 5.	0.422
LEUTX	DUXA	ENSP00000380053	ENSP00000452398	Leucine twenty homeobox.	Double homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family.	0.749
LEUTX	DUXB	ENSP00000380053	ENSP00000491301	Leucine twenty homeobox.	Double homeobox B.	0.757
LEUTX	H3Y1	ENSP00000380053	ENSP00000496014	Leucine twenty homeobox.	Histone H3.Y; Primate-specific variant histone H3, which constitutes a core component of nucleosomes. Histone H3.Y-containing nucleosomes accumulate around transcription start sites and have flexible DNA ends, suggesting that they form relaxed chromatin that allows transcription factor access. Histone H1 binds less efficiently to histone H3.Y-containing nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA repl [...]	0.470
LEUTX	MBD3L2	ENSP00000380053	ENSP00000370800	Leucine twenty homeobox.	methyl-CpG binding domain protein 3 like 2; Belongs to the MBD3L family.	0.745