node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MRPL12 | MRPL17 | ENSP00000333837 | ENSP00000288937 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein L17. | 0.999 |
MRPL12 | MRPL27 | ENSP00000333837 | ENSP00000225969 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein L27. | 0.999 |
MRPL12 | MRPL32 | ENSP00000333837 | ENSP00000223324 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.999 |
MRPL12 | MRPL33 | ENSP00000333837 | ENSP00000296102 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein L33. | 0.999 |
MRPL12 | MRPL58 | ENSP00000333837 | ENSP00000301585 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. | 0.999 |
MRPL12 | MRPS9 | ENSP00000333837 | ENSP00000258455 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Mitochondrial ribosomal protein S9. | 0.999 |
MRPL12 | RPL35 | ENSP00000333837 | ENSP00000259469 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | 60S ribosomal protein L35; Component of the large ribosomal subunit. | 0.999 |
MRPL12 | RPS11 | ENSP00000333837 | ENSP00000270625 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. | 0.999 |
MRPL12 | RPS3 | ENSP00000333837 | ENSP00000278572 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro- 8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] | 0.999 |
MRPL12 | TUFM | ENSP00000333837 | ENSP00000322439 | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.999 |
MRPL17 | MRPL12 | ENSP00000288937 | ENSP00000333837 | Mitochondrial ribosomal protein L17. | 39S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family. | 0.999 |
MRPL17 | MRPL27 | ENSP00000288937 | ENSP00000225969 | Mitochondrial ribosomal protein L17. | Mitochondrial ribosomal protein L27. | 0.999 |
MRPL17 | MRPL32 | ENSP00000288937 | ENSP00000223324 | Mitochondrial ribosomal protein L17. | Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.999 |
MRPL17 | MRPL33 | ENSP00000288937 | ENSP00000296102 | Mitochondrial ribosomal protein L17. | Mitochondrial ribosomal protein L33. | 0.999 |
MRPL17 | MRPL58 | ENSP00000288937 | ENSP00000301585 | Mitochondrial ribosomal protein L17. | Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes. | 0.992 |
MRPL17 | MRPS9 | ENSP00000288937 | ENSP00000258455 | Mitochondrial ribosomal protein L17. | Mitochondrial ribosomal protein S9. | 0.999 |
MRPL17 | RPL35 | ENSP00000288937 | ENSP00000259469 | Mitochondrial ribosomal protein L17. | 60S ribosomal protein L35; Component of the large ribosomal subunit. | 0.999 |
MRPL17 | RPS11 | ENSP00000288937 | ENSP00000270625 | Mitochondrial ribosomal protein L17. | Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. | 0.999 |
MRPL17 | RPS3 | ENSP00000288937 | ENSP00000278572 | Mitochondrial ribosomal protein L17. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro- 8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protei [...] | 0.999 |
MRPL17 | TUFM | ENSP00000288937 | ENSP00000322439 | Mitochondrial ribosomal protein L17. | Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.999 |