STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM212Transmembrane protein 212. (194 aa)    
Predicted Functional Partners:
CFAP54
Cilia- and flagella-associated protein 54; Required for assembly and function of cilia and flagella.
   
  
 0.980
WDPCP
WD repeat-containing and planar cell polarity effector protein fritz homolog; Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity).
   
    0.783
ADAMTSL3
ADAMTS-like protein 3; ADAMTS like 3.
   
    0.762
FSIP2
Fibrous sheath-interacting protein 2; Plays a role in spermatogenesis.
   
 
 0.704
FAM216B
Protein FAM216B; Family with sequence similarity 216 member B; Belongs to the FAM216 family.
   
  
 0.575
DYNLRB2
Dynein light chain roadblock-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
   
  
 0.565
TBC1D8B
TBC1 domain family member 8B; Involved in vesicular recycling, probably as a RAB11B GTPase- activating protein.
   
  
 0.559
MAB21L3
Protein mab-21-like 3; Mab-21 like 3.
   
  
 0.558
TMEM45A
Transmembrane protein 45A.
   
  
 0.543
C12orf50
Uncharacterized protein C12orf50; Chromosome 12 open reading frame 50.
   
    0.533
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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