STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LCE1ALate cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum. (110 aa)    
Predicted Functional Partners:
LCE2B
Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.
   
 0.999
LCE2D
Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.
   
 0.999
LCE2C
Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.
   
 0.990
LCE1D
Late cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum.
   
 
 0.989
LCE1B
Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.
   
 0.979
LCE6A
Late cornified envelope protein 6A; Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE family.
   
 
 0.978
LCE5A
Late cornified envelope protein 5A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.
   
 0.971
LCE4A
Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.
   
 0.964
LCE1F
Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.
   
 0.958
LCE3C
Late cornified envelope protein 3C; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.
   
 
 0.946
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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