| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C5orf38 | VSTM2B | ENSP00000334267 | ENSP00000335038 | Protein CEI; Chromosome 5 open reading frame 38. | V-set and transmembrane domain containing 2B. | 0.447 |
| CRTAC1 | VSTM2B | ENSP00000359629 | ENSP00000335038 | Cartilage acidic protein 1. | V-set and transmembrane domain containing 2B. | 0.438 |
| DOC2B | VSTM2B | ENSP00000482950 | ENSP00000335038 | Double C2-like domain-containing protein beta; Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium- dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium- triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma memb [...] | V-set and transmembrane domain containing 2B. | 0.504 |
| FXYD7 | VSTM2B | ENSP00000270310 | ENSP00000335038 | FXYD domain containing ion transport regulator 7; Belongs to the FXYD family. | V-set and transmembrane domain containing 2B. | 0.486 |
| LMCD1 | VSTM2B | ENSP00000157600 | ENSP00000335038 | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6- mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway. | V-set and transmembrane domain containing 2B. | 0.446 |
| OR6S1 | VSTM2B | ENSP00000313110 | ENSP00000335038 | Olfactory receptor 6S1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | V-set and transmembrane domain containing 2B. | 0.506 |
| POP4 | VSTM2B | ENSP00000465213 | ENSP00000335038 | Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. | V-set and transmembrane domain containing 2B. | 0.437 |
| TMCC1 | VSTM2B | ENSP00000376930 | ENSP00000335038 | Transmembrane and coiled-coil domains protein 1; Endoplasmic reticulum membrane protein that promotes endoplasmic reticulum-associated endosome fission. Localizes to contact sites between the endoplasmic reticulum and endosomes and acts by promoting recruitment of the endoplasmic reticulum to endosome tubules for fission. Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane. Belongs to the TEX28 family. | V-set and transmembrane domain containing 2B. | 0.447 |
| VSTM2B | C5orf38 | ENSP00000335038 | ENSP00000334267 | V-set and transmembrane domain containing 2B. | Protein CEI; Chromosome 5 open reading frame 38. | 0.447 |
| VSTM2B | CRTAC1 | ENSP00000335038 | ENSP00000359629 | V-set and transmembrane domain containing 2B. | Cartilage acidic protein 1. | 0.438 |
| VSTM2B | DOC2B | ENSP00000335038 | ENSP00000482950 | V-set and transmembrane domain containing 2B. | Double C2-like domain-containing protein beta; Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium- dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium- triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma memb [...] | 0.504 |
| VSTM2B | FXYD7 | ENSP00000335038 | ENSP00000270310 | V-set and transmembrane domain containing 2B. | FXYD domain containing ion transport regulator 7; Belongs to the FXYD family. | 0.486 |
| VSTM2B | LMCD1 | ENSP00000335038 | ENSP00000157600 | V-set and transmembrane domain containing 2B. | LIM and cysteine-rich domains protein 1; Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6- mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway. | 0.446 |
| VSTM2B | OR6S1 | ENSP00000335038 | ENSP00000313110 | V-set and transmembrane domain containing 2B. | Olfactory receptor 6S1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.506 |
| VSTM2B | POP4 | ENSP00000335038 | ENSP00000465213 | V-set and transmembrane domain containing 2B. | Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. | 0.437 |
| VSTM2B | TMCC1 | ENSP00000335038 | ENSP00000376930 | V-set and transmembrane domain containing 2B. | Transmembrane and coiled-coil domains protein 1; Endoplasmic reticulum membrane protein that promotes endoplasmic reticulum-associated endosome fission. Localizes to contact sites between the endoplasmic reticulum and endosomes and acts by promoting recruitment of the endoplasmic reticulum to endosome tubules for fission. Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane. Belongs to the TEX28 family. | 0.447 |
| VSTM2B | WHRN | ENSP00000335038 | ENSP00000354623 | V-set and transmembrane domain containing 2B. | Whirlin; Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear. In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport. | 0.435 |
| VSTM2B | ZNF536 | ENSP00000335038 | ENSP00000347730 | V-set and transmembrane domain containing 2B. | Zinc finger protein 536; May be involved in transcriptional regulation. Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA-3'; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.441 |
| WHRN | VSTM2B | ENSP00000354623 | ENSP00000335038 | Whirlin; Involved in hearing and vision as member of the USH2 complex. Necessary for elongation and maintenance of inner and outer hair cell stereocilia in the organ of Corti in the inner ear. Involved in the maintenance of the hair bundle ankle region, which connects stereocilia in cochlear hair cells of the inner ear. In retina photoreceptors, required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport. | V-set and transmembrane domain containing 2B. | 0.435 |
| ZNF536 | VSTM2B | ENSP00000347730 | ENSP00000335038 | Zinc finger protein 536; May be involved in transcriptional regulation. Recognizes and binds 2 copies of the core DNA sequence 5'-CCCCCA-3'; Belongs to the krueppel C2H2-type zinc-finger protein family. | V-set and transmembrane domain containing 2B. | 0.441 |