C7orf57 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf120	C10orf53	ENSP00000331012	ENSP00000363226	Uncharacterized protein C10orf120; Chromosome 10 open reading frame 120.	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	0.570
C10orf120	C7orf31	ENSP00000331012	ENSP00000283905	Uncharacterized protein C10orf120; Chromosome 10 open reading frame 120.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.675
C10orf120	C7orf57	ENSP00000331012	ENSP00000335500	Uncharacterized protein C10orf120; Chromosome 10 open reading frame 120.	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	0.569
C10orf53	C10orf120	ENSP00000363226	ENSP00000331012	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Uncharacterized protein C10orf120; Chromosome 10 open reading frame 120.	0.570
C10orf53	C7orf31	ENSP00000363226	ENSP00000283905	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.530
C10orf53	C7orf57	ENSP00000363226	ENSP00000335500	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	0.491
C7orf31	C10orf120	ENSP00000283905	ENSP00000331012	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Uncharacterized protein C10orf120; Chromosome 10 open reading frame 120.	0.675
C7orf31	C10orf53	ENSP00000283905	ENSP00000363226	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	0.530
C7orf31	C7orf57	ENSP00000283905	ENSP00000335500	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	0.511
C7orf31	CFAP45	ENSP00000283905	ENSP00000357079	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Cilia and flagella associated protein 45.	0.832
C7orf31	PPP1R32	ENSP00000283905	ENSP00000344140	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	Protein phosphatase 1 regulatory subunit 32.	0.731
C7orf57	C10orf120	ENSP00000335500	ENSP00000331012	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	Uncharacterized protein C10orf120; Chromosome 10 open reading frame 120.	0.569
C7orf57	C10orf53	ENSP00000335500	ENSP00000363226	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	UPF0728 protein C10orf53; Chromosome 10 open reading frame 53.	0.491
C7orf57	C7orf31	ENSP00000335500	ENSP00000283905	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.	0.511
C7orf57	CFAP45	ENSP00000335500	ENSP00000357079	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	Cilia and flagella associated protein 45.	0.501
C7orf57	FAM221B	ENSP00000335500	ENSP00000415299	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	Protein FAM221B; Family with sequence similarity 221 member B.	0.451
C7orf57	MAPK15	ENSP00000335500	ENSP00000337691	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	Mitogen-activated protein kinase 15; Atypical MAPK protein that regulates several process such as autophagy, ciliogenesis, protein trafficking/secretion and genome integrity, in a kinase activity-dependent manner. Controls both, basal and starvation-induced autophagy throught its interaction with GABARAP, MAP1LC3B and GABARAPL1 leading to autophagosome formation, SQSTM1 degradation and reduced MAP1LC3B inhibitory phosphorylation. Regulates primary cilium formation and the localization of ciliary proteins involved in cilium structure, transport, and signaling. Prevents the relocation of [...]	0.433
C7orf57	PLEKHH1	ENSP00000335500	ENSP00000330278	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	Pleckstrin homology, MyTH4 and FERM domain containing H1.	0.450
C7orf57	PPP1R32	ENSP00000335500	ENSP00000344140	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	Protein phosphatase 1 regulatory subunit 32.	0.552
C7orf57	SUN3	ENSP00000335500	ENSP00000297325	Uncharacterized protein C7orf57; Chromosome 7 open reading frame 57.	SUN domain-containing protein 3; As a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as [...]	0.628