TCP11L1 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC73	DEPDC7	ENSP00000335325	ENSP00000241051	Coiled-coil domain containing 73.	DEP domain containing 7; Belongs to the DEPDC7 family.	0.516
CCDC73	PRRG4	ENSP00000335325	ENSP00000257836	Coiled-coil domain containing 73.	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family.	0.622
CCDC73	QSER1	ENSP00000335325	ENSP00000382241	Coiled-coil domain containing 73.	Glutamine and serine rich 1.	0.611
CCDC73	TCP11L1	ENSP00000335325	ENSP00000335595	Coiled-coil domain containing 73.	T-complex protein 11-like protein 1; T-complex 11 like 1.	0.642
DEPDC7	CCDC73	ENSP00000241051	ENSP00000335325	DEP domain containing 7; Belongs to the DEPDC7 family.	Coiled-coil domain containing 73.	0.516
DEPDC7	PRRG4	ENSP00000241051	ENSP00000257836	DEP domain containing 7; Belongs to the DEPDC7 family.	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family.	0.443
DEPDC7	QSER1	ENSP00000241051	ENSP00000382241	DEP domain containing 7; Belongs to the DEPDC7 family.	Glutamine and serine rich 1.	0.542
DEPDC7	TCP11L1	ENSP00000241051	ENSP00000335595	DEP domain containing 7; Belongs to the DEPDC7 family.	T-complex protein 11-like protein 1; T-complex 11 like 1.	0.712
PRRG4	CCDC73	ENSP00000257836	ENSP00000335325	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family.	Coiled-coil domain containing 73.	0.622
PRRG4	DEPDC7	ENSP00000257836	ENSP00000241051	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family.	DEP domain containing 7; Belongs to the DEPDC7 family.	0.443
PRRG4	QSER1	ENSP00000257836	ENSP00000382241	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family.	Glutamine and serine rich 1.	0.785
PRRG4	TCP11L1	ENSP00000257836	ENSP00000335595	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family.	T-complex protein 11-like protein 1; T-complex 11 like 1.	0.585
QSER1	CCDC73	ENSP00000382241	ENSP00000335325	Glutamine and serine rich 1.	Coiled-coil domain containing 73.	0.611
QSER1	DEPDC7	ENSP00000382241	ENSP00000241051	Glutamine and serine rich 1.	DEP domain containing 7; Belongs to the DEPDC7 family.	0.542
QSER1	PRRG4	ENSP00000382241	ENSP00000257836	Glutamine and serine rich 1.	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family.	0.785
QSER1	TCP11L1	ENSP00000382241	ENSP00000335595	Glutamine and serine rich 1.	T-complex protein 11-like protein 1; T-complex 11 like 1.	0.616
TCP11L1	CCDC73	ENSP00000335595	ENSP00000335325	T-complex protein 11-like protein 1; T-complex 11 like 1.	Coiled-coil domain containing 73.	0.642
TCP11L1	DEPDC7	ENSP00000335595	ENSP00000241051	T-complex protein 11-like protein 1; T-complex 11 like 1.	DEP domain containing 7; Belongs to the DEPDC7 family.	0.712
TCP11L1	PRRG4	ENSP00000335595	ENSP00000257836	T-complex protein 11-like protein 1; T-complex 11 like 1.	Transmembrane gamma-carboxyglutamic acid protein 4; May control axon guidance across the CNS. Prevents the delivery of ROBO1 at the cell surface and downregulates its expression ; Belongs to the commissureless family.	0.585
TCP11L1	QSER1	ENSP00000335595	ENSP00000382241	T-complex protein 11-like protein 1; T-complex 11 like 1.	Glutamine and serine rich 1.	0.616