node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKAP4 | CATSPER1 | ENSP00000351327 | ENSP00000309052 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | Cation channel sperm-associated protein 1; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. | 0.494 |
AKAP4 | CRISP2 | ENSP00000351327 | ENSP00000484609 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | 0.574 |
AKAP4 | PATE1 | ENSP00000351327 | ENSP00000307164 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | Prostate and testis expressed 1; Belongs to the PATE family. | 0.449 |
AKAP4 | PGK2 | ENSP00000351327 | ENSP00000305995 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | Phosphoglycerate kinase 2; Essential for sperm motility and male fertility. Not required for the completion of spermatogenesis (By similarity); Belongs to the phosphoglycerate kinase family. | 0.451 |
CATSPER1 | AKAP4 | ENSP00000309052 | ENSP00000351327 | Cation channel sperm-associated protein 1; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | 0.494 |
CATSPER1 | CRISP2 | ENSP00000309052 | ENSP00000484609 | Cation channel sperm-associated protein 1; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | 0.750 |
CRISP2 | AKAP4 | ENSP00000484609 | ENSP00000351327 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility; Belongs to the AKAP110 family. | 0.574 |
CRISP2 | CATSPER1 | ENSP00000484609 | ENSP00000309052 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Cation channel sperm-associated protein 1; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. | 0.750 |
CRISP2 | CRISP3 | ENSP00000484609 | ENSP00000389026 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Cysteine rich secretory protein 3; Belongs to the CRISP family. | 0.666 |
CRISP2 | GART | ENSP00000484609 | ENSP00000371253 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | 0.831 |
CRISP2 | GGNBP2 | ENSP00000484609 | ENSP00000478220 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Gametogenetin-binding protein 2; May be involved in spermatogenesis. | 0.579 |
CRISP2 | IL4I1 | ENSP00000484609 | ENSP00000472474 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | L-amino-acid oxidase; Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity). | 0.657 |
CRISP2 | LTA4H | ENSP00000484609 | ENSP00000228740 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Leukotriene A-4 hydrolase; Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. | 0.591 |
CRISP2 | PATE1 | ENSP00000484609 | ENSP00000307164 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Prostate and testis expressed 1; Belongs to the PATE family. | 0.562 |
CRISP2 | PGK2 | ENSP00000484609 | ENSP00000305995 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Phosphoglycerate kinase 2; Essential for sperm motility and male fertility. Not required for the completion of spermatogenesis (By similarity); Belongs to the phosphoglycerate kinase family. | 0.821 |
CRISP2 | PLB1 | ENSP00000484609 | ENSP00000330442 | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | Phospholipase B1, membrane-associated; Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity). | 0.655 |
CRISP3 | CRISP2 | ENSP00000389026 | ENSP00000484609 | Cysteine rich secretory protein 3; Belongs to the CRISP family. | Cysteine-rich secretory protein 2; May regulate some ion channels' activity and therebye regulate calcium fluxes during sperm capacitation. | 0.666 |
CRISP3 | GART | ENSP00000389026 | ENSP00000371253 | Cysteine rich secretory protein 3; Belongs to the CRISP family. | Trifunctional purine biosynthetic protein adenosine-3; Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase; In the central section; belongs to the AIR synthase family. | 0.831 |
CRISP3 | IL4I1 | ENSP00000389026 | ENSP00000472474 | Cysteine rich secretory protein 3; Belongs to the CRISP family. | L-amino-acid oxidase; Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation (By similarity). | 0.625 |
CRISP3 | LTA4H | ENSP00000389026 | ENSP00000228740 | Cysteine rich secretory protein 3; Belongs to the CRISP family. | Leukotriene A-4 hydrolase; Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. | 0.550 |