node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYLC2 | SPATA31E1 | ENSP00000420256 | ENSP00000322640 | Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation. | Spermatogenesis-associated protein 31E1; May play a role in spermatogenesis; Belongs to the SPATA31 family. | 0.553 |
CYLC2 | ZNF433 | ENSP00000420256 | ENSP00000339767 | Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation. | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.407 |
OR2D3 | ZNF433 | ENSP00000320560 | ENSP00000339767 | Olfactory receptor 2D3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.432 |
RCCD1 | TMEM220 | ENSP00000377801 | ENSP00000339830 | RCC1 domain-containing protein 1; Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8. | Transmembrane protein 220. | 0.433 |
RCCD1 | ZNF433 | ENSP00000377801 | ENSP00000339767 | RCC1 domain-containing protein 1; Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8. | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.425 |
SPATA31E1 | CYLC2 | ENSP00000322640 | ENSP00000420256 | Spermatogenesis-associated protein 31E1; May play a role in spermatogenesis; Belongs to the SPATA31 family. | Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation. | 0.553 |
SPATA31E1 | ZNF433 | ENSP00000322640 | ENSP00000339767 | Spermatogenesis-associated protein 31E1; May play a role in spermatogenesis; Belongs to the SPATA31 family. | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.447 |
TMEM220 | RCCD1 | ENSP00000339830 | ENSP00000377801 | Transmembrane protein 220. | RCC1 domain-containing protein 1; Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8. | 0.433 |
TMEM220 | ZNF433 | ENSP00000339830 | ENSP00000339767 | Transmembrane protein 220. | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.475 |
TRIM28 | ZNF433 | ENSP00000253024 | ENSP00000339767 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.570 |
ZNF433 | CYLC2 | ENSP00000339767 | ENSP00000420256 | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Cylicin-2; Possible architectural role during spermatogenesis. May be involved in spermatid differentiation. | 0.407 |
ZNF433 | OR2D3 | ENSP00000339767 | ENSP00000320560 | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Olfactory receptor 2D3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.432 |
ZNF433 | RCCD1 | ENSP00000339767 | ENSP00000377801 | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | RCC1 domain-containing protein 1; Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8. | 0.425 |
ZNF433 | SPATA31E1 | ENSP00000339767 | ENSP00000322640 | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Spermatogenesis-associated protein 31E1; May play a role in spermatogenesis; Belongs to the SPATA31 family. | 0.447 |
ZNF433 | TMEM220 | ENSP00000339767 | ENSP00000339830 | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transmembrane protein 220. | 0.475 |
ZNF433 | TRIM28 | ENSP00000339767 | ENSP00000253024 | Zinc finger protein 433; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.570 |