STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM202Transmembrane protein 202. (273 aa)    
Predicted Functional Partners:
FAM221B
Protein FAM221B; Family with sequence similarity 221 member B.
      
 0.646
SPATA31D1
Spermatogenesis-associated protein 31D1; May play a role in spermatogenesis; Belongs to the SPATA31 family.
   
  
 0.587
OR4D10
Olfactory receptor 4D10; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.563
NT5C1B-RDH14
NT5C1B-RDH14 readthrough.
      
 0.537
NT5C1B
Cytosolic 5'-nucleotidase 1B; Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels (By similarity).
      
 0.516
SPACA1
Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis (By similarity). Important for male fertility.
   
  
 0.488
FNDC8
Fibronectin type III domain containing 8.
      
 0.480
CFAP45
Cilia and flagella associated protein 45.
      
 0.457
CABYR
Calcium-binding tyrosine phosphorylation-regulated protein; May function as a regulator of both motility- and head- associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.
      
 0.454
SPEM3
Uncharacterized protein SPEM3; SPEM family member 3.
      
 0.445
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.