node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BEX5 | SAXO2 | ENSP00000446054 | ENSP00000340445 | Protein BEX5; Brain expressed X-linked 5; Belongs to the BEX family. | Stabilizer of axonemal microtubules 2. | 0.579 |
CCDC65 | CFAP161 | ENSP00000312706 | ENSP00000286732 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | 0.549 |
CCDC65 | CFAP52 | ENSP00000312706 | ENSP00000339449 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | 0.597 |
CCDC65 | LRRC46 | ENSP00000312706 | ENSP00000269025 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46. | 0.409 |
CCDC65 | RSPH14 | ENSP00000312706 | ENSP00000216036 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | 0.636 |
CCDC65 | SAXO2 | ENSP00000312706 | ENSP00000340445 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Stabilizer of axonemal microtubules 2. | 0.474 |
CCDC65 | SNTN | ENSP00000312706 | ENSP00000341442 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Sentan; May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules. | 0.507 |
CCDC65 | TSNAXIP1 | ENSP00000312706 | ENSP00000457241 | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis. | 0.443 |
CFAP161 | CCDC65 | ENSP00000286732 | ENSP00000312706 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | 0.549 |
CFAP161 | CFAP52 | ENSP00000286732 | ENSP00000339449 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | 0.928 |
CFAP161 | LRRC46 | ENSP00000286732 | ENSP00000269025 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46. | 0.674 |
CFAP161 | RSPH14 | ENSP00000286732 | ENSP00000216036 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | 0.590 |
CFAP161 | SAXO2 | ENSP00000286732 | ENSP00000340445 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Stabilizer of axonemal microtubules 2. | 0.481 |
CFAP161 | TSNAXIP1 | ENSP00000286732 | ENSP00000457241 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Translin-associated factor X-interacting protein 1; Possible role in spermatogenesis. | 0.553 |
CFAP52 | CCDC65 | ENSP00000339449 | ENSP00000312706 | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | Dynein regulatory complex subunit 2; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (By similarity). Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. Belongs to the DRC2 family. | 0.597 |
CFAP52 | CFAP161 | ENSP00000339449 | ENSP00000286732 | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | 0.928 |
CFAP52 | LRRC46 | ENSP00000339449 | ENSP00000269025 | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46. | 0.540 |
CFAP52 | RSPH14 | ENSP00000339449 | ENSP00000216036 | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | 0.712 |
CFAP52 | SAXO2 | ENSP00000339449 | ENSP00000340445 | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | Stabilizer of axonemal microtubules 2. | 0.586 |
CFAP52 | SNTN | ENSP00000339449 | ENSP00000341442 | Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family. | Sentan; May be a component of the linker structure that bridges the ciliary membrane and peripheral singlet microtubules. | 0.420 |