Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARRDC2 | RAB3A | ENSP00000222250 | ENSP00000222256 | Arrestin domain containing 2; Belongs to the arrestin family. | Ras-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] | 0.425 |
| ARRDC2 | RASL11B | ENSP00000222250 | ENSP00000248706 | Arrestin domain containing 2; Belongs to the arrestin family. | Ras-like protein family member 11B; RAS like family 11 member B. | 0.449 |
| ARRDC2 | RHOF | ENSP00000222250 | ENSP00000267205 | Arrestin domain containing 2; Belongs to the arrestin family. | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology. | 0.427 |
| ARRDC2 | SYDE2 | ENSP00000222250 | ENSP00000340594 | Arrestin domain containing 2; Belongs to the arrestin family. | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.481 |
| C1orf52 | SYDE2 | ENSP00000419417 | ENSP00000340594 | UPF0690 protein C1orf52; Chromosome 1 open reading frame 52; Belongs to the UPF0690 family. | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.477 |
| CHRM5 | SYDE2 | ENSP00000372750 | ENSP00000340594 | Muscarinic acetylcholine receptor M5; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.474 |
| CNTROB | SYDE2 | ENSP00000369614 | ENSP00000340594 | Centrobin; Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis. | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.465 |
| GCM1 | SYDE2 | ENSP00000259803 | ENSP00000340594 | Chorion-specific transcription factor GCMa; Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development. | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.471 |
| PPP4R3A | SYDE2 | ENSP00000450864 | ENSP00000340594 | Serine/threonine-protein phosphatase 4 regulatory subunit 3A; Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on 'Ser-140' (gamma-H2AX) generated during DNA replication and required for DNA DSB repair. Belongs to the SMEK family. | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.512 |
| RAB3A | ARRDC2 | ENSP00000222256 | ENSP00000222250 | Ras-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] | Arrestin domain containing 2; Belongs to the arrestin family. | 0.425 |
| RAB3A | SYDE2 | ENSP00000222256 | ENSP00000340594 | Ras-related protein Rab-3A; Small GTP-binding protein that plays a central role in regulated exocytosis and secretion. Controls the recruitment, tethering and docking of secretory vesicles to the plasma membrane (By similarity). Upon stimulation, switches to its active GTP-bound form, cycles to vesicles and recruits effectors such as RIMS1, RIMS2, Rabphilin-3A/RPH3A, RPH3AL or SYTL4 to help the docking of vesicules onto the plasma membrane (By similarity). Upon GTP hydrolysis by GTPase-activating protein, dissociates from the vesicle membrane allowing the exocytosis to proceed (By simi [...] | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.477 |
| RAC1 | SYDE2 | ENSP00000348461 | ENSP00000340594 | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.645 |
| RASL11B | ARRDC2 | ENSP00000248706 | ENSP00000222250 | Ras-like protein family member 11B; RAS like family 11 member B. | Arrestin domain containing 2; Belongs to the arrestin family. | 0.449 |
| RASL11B | RHOF | ENSP00000248706 | ENSP00000267205 | Ras-like protein family member 11B; RAS like family 11 member B. | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology. | 0.442 |
| RASL11B | SYDE2 | ENSP00000248706 | ENSP00000340594 | Ras-like protein family member 11B; RAS like family 11 member B. | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.500 |
| RHOF | ARRDC2 | ENSP00000267205 | ENSP00000222250 | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology. | Arrestin domain containing 2; Belongs to the arrestin family. | 0.427 |
| RHOF | RASL11B | ENSP00000267205 | ENSP00000248706 | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology. | Ras-like protein family member 11B; RAS like family 11 member B. | 0.442 |
| RHOF | SYDE2 | ENSP00000267205 | ENSP00000340594 | Rho-related GTP-binding protein RhoF; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology. | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.484 |
| SYDE2 | ARRDC2 | ENSP00000340594 | ENSP00000222250 | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | Arrestin domain containing 2; Belongs to the arrestin family. | 0.481 |
| SYDE2 | C1orf52 | ENSP00000340594 | ENSP00000419417 | Rho GTPase-activating protein SYDE2; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | UPF0690 protein C1orf52; Chromosome 1 open reading frame 52; Belongs to the UPF0690 family. | 0.477 |
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