node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD10 | POTEH | ENSP00000267339 | ENSP00000340610 | Ankyrin repeat domain 10. | POTE ankyrin domain family member H. | 0.474 |
ANKRD22 | ANKRD46 | ENSP00000360998 | ENSP00000429015 | Ankyrin repeat domain 22. | Ankyrin repeat domain 46. | 0.445 |
ANKRD22 | ASB5 | ENSP00000360998 | ENSP00000296525 | Ankyrin repeat domain 22. | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity); Belongs to the ankyrin SOCS box (ASB) family. | 0.413 |
ANKRD22 | ASZ1 | ENSP00000360998 | ENSP00000284629 | Ankyrin repeat domain 22. | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...] | 0.401 |
ANKRD22 | MTPN | ENSP00000360998 | ENSP00000376800 | Ankyrin repeat domain 22. | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family. | 0.416 |
ANKRD22 | POTEH | ENSP00000360998 | ENSP00000340610 | Ankyrin repeat domain 22. | POTE ankyrin domain family member H. | 0.489 |
ANKRD46 | ANKRD22 | ENSP00000429015 | ENSP00000360998 | Ankyrin repeat domain 46. | Ankyrin repeat domain 22. | 0.445 |
ANKRD46 | ASB11 | ENSP00000429015 | ENSP00000417914 | Ankyrin repeat domain 46. | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | 0.427 |
ANKRD46 | ASB12 | ENSP00000429015 | ENSP00000355195 | Ankyrin repeat domain 46. | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.402 |
ANKRD46 | ASB5 | ENSP00000429015 | ENSP00000296525 | Ankyrin repeat domain 46. | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity); Belongs to the ankyrin SOCS box (ASB) family. | 0.414 |
ANKRD46 | ASZ1 | ENSP00000429015 | ENSP00000284629 | Ankyrin repeat domain 46. | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...] | 0.500 |
ANKRD46 | MTPN | ENSP00000429015 | ENSP00000376800 | Ankyrin repeat domain 46. | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family. | 0.436 |
ANKRD46 | POTEH | ENSP00000429015 | ENSP00000340610 | Ankyrin repeat domain 46. | POTE ankyrin domain family member H. | 0.495 |
ANKRD49 | ASZ1 | ENSP00000440396 | ENSP00000284629 | Ankyrin repeat domain-containing protein 49; Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway (By similarity). | Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1; Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the p [...] | 0.408 |
ANKRD49 | MTPN | ENSP00000440396 | ENSP00000376800 | Ankyrin repeat domain-containing protein 49; Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway (By similarity). | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family. | 0.449 |
ANKRD49 | POTEH | ENSP00000440396 | ENSP00000340610 | Ankyrin repeat domain-containing protein 49; Induces HBG1 expression. May have a role in spermatogenesis where it promotes autophagy in response to serum starvation, via the NF-kappaB pathway (By similarity). | POTE ankyrin domain family member H. | 0.472 |
ASB11 | ANKRD46 | ENSP00000417914 | ENSP00000429015 | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | Ankyrin repeat domain 46. | 0.427 |
ASB11 | MTPN | ENSP00000417914 | ENSP00000376800 | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family. | 0.449 |
ASB11 | POTEH | ENSP00000417914 | ENSP00000340610 | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | POTE ankyrin domain family member H. | 0.490 |
ASB12 | ANKRD46 | ENSP00000355195 | ENSP00000429015 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ankyrin repeat domain 46. | 0.402 |