node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C15orf61 | C15orf62 | ENSP00000342254 | ENSP00000341178 | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | 0.630 |
C15orf61 | C3orf33 | ENSP00000342254 | ENSP00000342512 | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | Protein C3orf33; [Isoform 2]: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane. | 0.701 |
C15orf61 | DNAJC11 | ENSP00000342254 | ENSP00000366800 | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family. | 0.401 |
C15orf61 | DNAJC4 | ENSP00000342254 | ENSP00000320548 | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | DnaJ heat shock protein family member C4. | 0.455 |
C15orf61 | GFM2 | ENSP00000342254 | ENSP00000427004 | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. | 0.447 |
C15orf61 | MRPL53 | ENSP00000342254 | ENSP00000258105 | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | Mitochondrial ribosomal protein L53. | 0.459 |
C15orf61 | MRPS18A | ENSP00000342254 | ENSP00000361206 | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | Mitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily. | 0.458 |
C15orf61 | MTERF4 | ENSP00000342254 | ENSP00000480378 | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | Transcription termination factor 4, mitochondrial; Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S); Belongs to the mTERF family. | 0.426 |
C15orf62 | C15orf61 | ENSP00000341178 | ENSP00000342254 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | 0.630 |
C15orf62 | C3orf33 | ENSP00000341178 | ENSP00000342512 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | Protein C3orf33; [Isoform 2]: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane. | 0.626 |
C15orf62 | DNAJC11 | ENSP00000341178 | ENSP00000366800 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | DnaJ homolog subfamily C member 11; [Isoform 1]: Required for mitochondrial inner membrane organization. Seems to function through its association with the MICOS complex and the mitochondrial outer membrane sorting assembly machinery (SAM) complex; Belongs to the DNAJC11 family. | 0.431 |
C15orf62 | DNAJC17 | ENSP00000341178 | ENSP00000220496 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription. | 0.585 |
C15orf62 | DNAJC4 | ENSP00000341178 | ENSP00000320548 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | DnaJ heat shock protein family member C4. | 0.481 |
C15orf62 | GFM2 | ENSP00000341178 | ENSP00000427004 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. | 0.478 |
C15orf62 | MRPL53 | ENSP00000341178 | ENSP00000258105 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | Mitochondrial ribosomal protein L53. | 0.486 |
C15orf62 | MRPS18A | ENSP00000341178 | ENSP00000361206 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | Mitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily. | 0.487 |
C15orf62 | MTERF4 | ENSP00000341178 | ENSP00000480378 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | Transcription termination factor 4, mitochondrial; Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S); Belongs to the mTERF family. | 0.461 |
C15orf62 | ZFYVE19 | ENSP00000341178 | ENSP00000347498 | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | Abscission/NoCut checkpoint regulator; Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission. | 0.479 |
C3orf33 | C15orf61 | ENSP00000342512 | ENSP00000342254 | Protein C3orf33; [Isoform 2]: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane. | Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61. | 0.701 |
C3orf33 | C15orf62 | ENSP00000342512 | ENSP00000341178 | Protein C3orf33; [Isoform 2]: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane. | Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62. | 0.626 |