Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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C6orf132Uncharacterized protein C6orf132; Chromosome 6 open reading frame 132. (1188 aa)    
Predicted Functional Partners:
RDX
Radixin; Probably plays a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
    
   0.736
C8orf48
Uncharacterized protein C8orf48; Chromosome 8 open reading frame 48.
  
   
 0.569
TTC9
Tetratricopeptide repeat domain 9; Belongs to the TTC9 family.
   
  
 0.507
TAF8
Transcription initiation factor TFIID subunit 8; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription. Plays a role in the differentiation of preadipocyte fibroblasts to adipocytes, however, does not seem to play a role in differentiation of myoblasts. Required for the integration of TAF10 in the TAF complex. May be important for survival of cells of the inner cell mass which constitute the pluripotent cell population of the early embryo (By similarity). Be [...]
   
  
 0.504
INSYN2B
Protein INSYN2B; Inhibitory synaptic factor family member 2B; Belongs to the INSYN2 family.
    
 
 0.504
TRERF1
Transcriptional-regulating factor 1; Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.
      
 0.490
SMIM3
Small integral membrane protein 3.
      
 0.477
C1orf210
Type III endosome membrane protein TEMP; May be involved in membrane trafficking between endosomes and plasma membrane.
   
 
 0.458
CIT
Citron Rho-interacting kinase; Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.
    
   0.457
TRNP1
TMF-regulated nuclear protein 1; DNA-binding factor that regulates the expression of a subset of genes and plays a key role in tangential, radial, and lateral expansion of the brain neocortex. Regulates neural stem cells proliferation and the production of intermediate neural progenitors and basal radial glial cells affecting the process of cerebral cortex gyrification. May control the proliferation rate of cells by regulating their progression through key cell-cycle transition points (By similarity).
  
    0.443
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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