node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C2orf16 | FAM111B | ENSP00000386190 | ENSP00000341565 | Uncharacterized protein C2orf16; Chromosome 2 open reading frame 16. | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | 0.483 |
CCDC73 | CDCP2 | ENSP00000335325 | ENSP00000489959 | Coiled-coil domain containing 73. | CUB domain containing protein 2. | 0.561 |
CCDC73 | FAM111B | ENSP00000335325 | ENSP00000341565 | Coiled-coil domain containing 73. | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | 0.450 |
CCDC73 | SCLT1 | ENSP00000335325 | ENSP00000281142 | Coiled-coil domain containing 73. | Sodium channel and clathrin linker 1; Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity). | 0.458 |
CCDC73 | ZDBF2 | ENSP00000335325 | ENSP00000497308 | Coiled-coil domain containing 73. | DBF4-type zinc finger-containing protein 2; Zinc finger DBF-type containing 2. | 0.458 |
CDCP2 | CCDC73 | ENSP00000489959 | ENSP00000335325 | CUB domain containing protein 2. | Coiled-coil domain containing 73. | 0.561 |
CDCP2 | FAM111B | ENSP00000489959 | ENSP00000341565 | CUB domain containing protein 2. | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | 0.450 |
CDCP2 | SCLT1 | ENSP00000489959 | ENSP00000281142 | CUB domain containing protein 2. | Sodium channel and clathrin linker 1; Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity). | 0.451 |
CDCP2 | ZDBF2 | ENSP00000489959 | ENSP00000497308 | CUB domain containing protein 2. | DBF4-type zinc finger-containing protein 2; Zinc finger DBF-type containing 2. | 0.451 |
ELSPBP1 | FAM111B | ENSP00000340660 | ENSP00000341565 | Epididymal sperm-binding protein 1; Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity (By similarity); Belongs to the seminal plasma protein family. | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | 0.459 |
ESCO2 | FAM111B | ENSP00000306999 | ENSP00000341565 | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3. | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | 0.508 |
FAM111B | C2orf16 | ENSP00000341565 | ENSP00000386190 | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | Uncharacterized protein C2orf16; Chromosome 2 open reading frame 16. | 0.483 |
FAM111B | CCDC73 | ENSP00000341565 | ENSP00000335325 | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | Coiled-coil domain containing 73. | 0.450 |
FAM111B | CDCP2 | ENSP00000341565 | ENSP00000489959 | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | CUB domain containing protein 2. | 0.450 |
FAM111B | ELSPBP1 | ENSP00000341565 | ENSP00000340660 | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | Epididymal sperm-binding protein 1; Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity (By similarity); Belongs to the seminal plasma protein family. | 0.459 |
FAM111B | ESCO2 | ENSP00000341565 | ENSP00000306999 | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | N-acetyltransferase ESCO2; Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3. | 0.508 |
FAM111B | SCLT1 | ENSP00000341565 | ENSP00000281142 | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | Sodium channel and clathrin linker 1; Adapter protein that links SCN10A to clathrin. Regulates SCN10A channel activity, possibly by promoting channel internalization (By similarity). | 0.454 |
FAM111B | SET | ENSP00000341565 | ENSP00000361777 | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | Protein SET; Multitasking protein, involved in apoptosis, transcription, nucleosome assembly and histone chaperoning. Isoform 2 anti-apoptotic activity is mediated by inhibition of the GZMA-activated DNase, NME1. In the course of cytotoxic T-lymphocyte (CTL)-induced apoptosis, GZMA cleaves SET, disrupting its binding to NME1 and releasing NME1 inhibition. Isoform 1 and isoform 2 are potent inhibitors of protein phosphatase 2A. Isoform 1 and isoform 2 inhibit EP300/CREBBP and PCAF- mediated acetylation of histones (HAT) and nucleosomes, most probably by masking the accessibility of lysi [...] | 0.653 |
FAM111B | TMEM185B | ENSP00000341565 | ENSP00000453399 | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | Transmembrane protein 185B. | 0.447 |
FAM111B | ZDBF2 | ENSP00000341565 | ENSP00000497308 | Protein FAM111B; Family with sequence similarity 111 member B; Belongs to the FAM111 family. | DBF4-type zinc finger-containing protein 2; Zinc finger DBF-type containing 2. | 0.432 |