C15orf61 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C15orf61	C15orf62	ENSP00000342254	ENSP00000341178	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62.	0.603
C15orf61	C16orf91	ENSP00000342254	ENSP00000413100	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	Protein CCSMST1; Chromosome 16 open reading frame 91.	0.458
C15orf61	C3orf33	ENSP00000342254	ENSP00000342512	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	Protein C3orf33; [Isoform 2]: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane.	0.662
C15orf61	CTLA4	ENSP00000342254	ENSP00000497102	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.	0.502
C15orf61	DNAJC4	ENSP00000342254	ENSP00000320548	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	DnaJ heat shock protein family member C4.	0.453
C15orf61	GFM2	ENSP00000342254	ENSP00000427004	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.	0.461
C15orf61	IQCH	ENSP00000342254	ENSP00000336861	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	IQ domain-containing protein H; May play a regulatory role in spermatogenesis.	0.425
C15orf61	MRPS18A	ENSP00000342254	ENSP00000361206	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	Mitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily.	0.446
C15orf61	MTERF4	ENSP00000342254	ENSP00000480378	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	Transcription termination factor 4, mitochondrial; Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S); Belongs to the mTERF family.	0.442
C15orf61	TIPARP	ENSP00000342254	ENSP00000420612	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	Protein mono-ADP-ribosyltransferase TIPARP; ADP-ribosyltransferase that mediates mono-ADP-ribosylation of glutamate, aspartate and cysteine residues on target proteins. Acts as a negative regulator of AHR by mediating mono-ADP-ribosylation of AHR, leading to inhibit transcription activator activity of AHR.	0.457
C15orf62	C15orf61	ENSP00000341178	ENSP00000342254	Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62.	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	0.603
C15orf62	C3orf33	ENSP00000341178	ENSP00000342512	Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62.	Protein C3orf33; [Isoform 2]: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane.	0.612
C15orf62	DNAJC4	ENSP00000341178	ENSP00000320548	Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62.	DnaJ heat shock protein family member C4.	0.486
C15orf62	GFM2	ENSP00000341178	ENSP00000427004	Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62.	Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.	0.478
C15orf62	MRPS18A	ENSP00000341178	ENSP00000361206	Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62.	Mitochondrial ribosomal protein S18A; Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mL66 subfamily.	0.481
C15orf62	MTERF4	ENSP00000341178	ENSP00000480378	Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62.	Transcription termination factor 4, mitochondrial; Regulator of mitochondrial ribosome biogenesis and translation. Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S and targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit (39S); Belongs to the mTERF family.	0.446
C16orf91	C15orf61	ENSP00000413100	ENSP00000342254	Protein CCSMST1; Chromosome 16 open reading frame 91.	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	0.458
C3orf33	C15orf61	ENSP00000342512	ENSP00000342254	Protein C3orf33; [Isoform 2]: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane.	Uncharacterized protein C15orf61; Chromosome 15 open reading frame 61.	0.662
C3orf33	C15orf62	ENSP00000342512	ENSP00000341178	Protein C3orf33; [Isoform 2]: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane.	Uncharacterized protein C15orf62, mitochondrial; Chromosome 15 open reading frame 62.	0.612
C3orf33	DNAJC4	ENSP00000342512	ENSP00000320548	Protein C3orf33; [Isoform 2]: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane.	DnaJ heat shock protein family member C4.	0.449